What major product (from Figure #4) results from the following two- step reaction sequence (from Reaction Sequence # 4)? Reaction Sequence #4 МСРВА H* MAJOR PRODUCT? MeOH ерохide Figure #4 OH OMe OH Meo OH OH OMe OMe compound A compound B compound C compound D Hint: the reaction of the epoxide with methanol (MeOH) is performed under acidic conditions, so please make sure that you understand which carbon in the protonated 3-membered ring epoxide gets preferentially attacked by the methanol nucleophile. compound A compound B compound C compound D

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter24: Carboxylic Acids & Derivatives
Section: Chapter Questions
Problem 16CTQ
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Please draw the mechanism for the reaction

What major product (from Figure #4) results from the following two-
step reaction sequence (from Reaction Sequence #4)?
Reaction Sequence #4
МСРВА
H+
MAJOR PRODUCT?
МеОн
ерохide
Figure #4
OH
OMe
OH
MeO
OH
OH
OMe
OMe
compound A
compound B
compound C
compound D
Hint: the reaction of the epoxide with methanol (MeOH) is performed
under acidic conditions, so please make sure that you understand which
carbon in the protonated 3-membered ring epoxide gets preferentially
attacked by the methanol nucleophile.
compound A
compound B
compound C
compound D
Transcribed Image Text:What major product (from Figure #4) results from the following two- step reaction sequence (from Reaction Sequence #4)? Reaction Sequence #4 МСРВА H+ MAJOR PRODUCT? МеОн ерохide Figure #4 OH OMe OH MeO OH OH OMe OMe compound A compound B compound C compound D Hint: the reaction of the epoxide with methanol (MeOH) is performed under acidic conditions, so please make sure that you understand which carbon in the protonated 3-membered ring epoxide gets preferentially attacked by the methanol nucleophile. compound A compound B compound C compound D
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