What is the structure that best represents the following amino acid at pH = 10? H₂N A H₂N 요 NH₂ B OH is style w HN H₂N NH₂ NH₂ с NH3 H₂N NH₂ D OH

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Chapter1: Chemical Foundations
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**Question:**

What is the structure that best represents the following amino acid at pH = 10?

**Diagram Description:**

1. **Original Structure:**
   - The boxed structure shows the amino acid glutamine, with a carboxylic acid group (COOH), an amino group (NH2), and an additional amide group (NH2) on the side chain.

2. **Options:**

   **A.** Structure with both carboxyl groups as carboxylate ions (COO⁻) and the amide group unchanged (NH2).

   **B.** Structure with one carboxyl group as a carboxylate ion (COO⁻), the other carboxyl group unchanged (COOH), and the amino group as a protonated amine (NH3⁺).

   **C.** Structure with one carboxyl group as a carboxylate ion (COO⁻), the other unchanged (COOH), and the amino group as a protonated amine (NH3⁺).

   **D.** Structure with both carboxyl groups unchanged (COOH) and the amide group unchanged (NH2).

**Answer Options:**

- ○ A
- ○ B
- ○ C
- ○ D

**Explanation:**

At pH = 10, the carboxyl groups are predominantly in their deprotonated form (COO⁻), and the amine group is typically in its neutral form (NH2) in the side chain, while the alpha-amino group is protonated (NH3⁺). Thus, Option A represents the expected structure at this pH.
Transcribed Image Text:**Question:** What is the structure that best represents the following amino acid at pH = 10? **Diagram Description:** 1. **Original Structure:** - The boxed structure shows the amino acid glutamine, with a carboxylic acid group (COOH), an amino group (NH2), and an additional amide group (NH2) on the side chain. 2. **Options:** **A.** Structure with both carboxyl groups as carboxylate ions (COO⁻) and the amide group unchanged (NH2). **B.** Structure with one carboxyl group as a carboxylate ion (COO⁻), the other carboxyl group unchanged (COOH), and the amino group as a protonated amine (NH3⁺). **C.** Structure with one carboxyl group as a carboxylate ion (COO⁻), the other unchanged (COOH), and the amino group as a protonated amine (NH3⁺). **D.** Structure with both carboxyl groups unchanged (COOH) and the amide group unchanged (NH2). **Answer Options:** - ○ A - ○ B - ○ C - ○ D **Explanation:** At pH = 10, the carboxyl groups are predominantly in their deprotonated form (COO⁻), and the amine group is typically in its neutral form (NH2) in the side chain, while the alpha-amino group is protonated (NH3⁺). Thus, Option A represents the expected structure at this pH.
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