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What is the relative activity of the following mineralocorticoid drugs?   A. A>C>B>D B. A>B>C>D C. C>A>D>B D. D>C>B>A E. C>B>A>D

What is the relative activity of the following mineralocorticoid drugs?   A. A>C>B>D B. A>B>C>D C. C>A>D>B D. D>C>B>A E. C>B>A>D

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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What is the relative activity of the following mineralocorticoid drugs?

 

A. A>C>B>D

B. A>B>C>D

C. C>A>D>B

D. D>C>B>A

E. C>B>A>D

 

 

 

The image displays four chemical structures labeled A, B, C, and D. Each structure represents a complex organic molecule, likely forms of steroids, composed of rings and various functional groups. Here is a detailed breakdown: ### Structure A - **Backbone**: Four interconnected carbon rings. - **Functional Groups**: - Hydroxyl groups (OH) are attached at specific carbon atoms. - Additional methyl (CH₃) groups. - A double-bonded oxygen (carbonyl group) on one of the rings. ### Structure B - **Backbone**: Similar to structure A with four carbon rings. - **Functional Groups**: - Hydroxyl groups (OH) positioned differently than in structure A. - Presence of double bonds within the ring structure. ### Structure C - **Backbone**: Four-ringed structure akin to the previous molecules. - **Functional Groups**: - Positioned hydroxyl groups (OH). - Distinct locations of double bonds compared to structures A and B. ### Structure D - **Backbone**: Consists of the four-carbon ring pattern. - **Functional Groups**: - Hydroxyl group placement. - Presence of halogen atoms, indicated by F (fluorine), modifying the molecule distinctively. - Different pattern of carbonyl groups and double bonds. Each structure highlights variations in organic chemistry that can significantly affect molecular properties and biological activity.
Transcribed Image Text:The image displays four chemical structures labeled A, B, C, and D. Each structure represents a complex organic molecule, likely forms of steroids, composed of rings and various functional groups. Here is a detailed breakdown: ### Structure A - **Backbone**: Four interconnected carbon rings. - **Functional Groups**: - Hydroxyl groups (OH) are attached at specific carbon atoms. - Additional methyl (CH₃) groups. - A double-bonded oxygen (carbonyl group) on one of the rings. ### Structure B - **Backbone**: Similar to structure A with four carbon rings. - **Functional Groups**: - Hydroxyl groups (OH) positioned differently than in structure A. - Presence of double bonds within the ring structure. ### Structure C - **Backbone**: Four-ringed structure akin to the previous molecules. - **Functional Groups**: - Positioned hydroxyl groups (OH). - Distinct locations of double bonds compared to structures A and B. ### Structure D - **Backbone**: Consists of the four-carbon ring pattern. - **Functional Groups**: - Hydroxyl group placement. - Presence of halogen atoms, indicated by F (fluorine), modifying the molecule distinctively. - Different pattern of carbonyl groups and double bonds. Each structure highlights variations in organic chemistry that can significantly affect molecular properties and biological activity.
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