What is the purpose of the sequence sequences “MDYKDDDA” and “HHHHHH” at the N- and C-termini respectively?
What is the purpose of the sequence sequences “MDYKDDDA” and “HHHHHH” at the N- and C-termini respectively?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Figure 1 represents the amino acid sequence of a G-protein coupled receptor (GPCR) as determine by mass spectrometry.
*Figure 1 is shown as in the added image.
Figure 1: The amino acid sequence of a GPCR as determined by mass spectrometry.
a) What is the purpose of the sequence sequences “MDYKDDDA” and “HHHHHH” at the N- and C-termini respectively?
![TMH1
10
20
30
40
50
HDYRDDDAMS OONTSGDCLF DGVNELMKTL QFAVHIPTFV LGLLLNLLAI
TMH2
60
70
80
90
100
HGFSTFLKNR WPDYAATSIY MINLAVFDLL LVLSLPFKMV LSQVOSPFPS
TMH3
110
120
130
140
150
LCTLVECLYF VSMYGSVFTI CFISMDRFLA IRYPLLVSHL RSPRKIFGIC
TMH4
THH5
160
170
180
190
200
CTIWVLVWTG SIPIYSFHGK VEKYMCFHNM SDDTHSAKVE FPLEVFGFLL
THH6
210
220
230
240
250
PHGIMGFCCS RSIHILLGRR DHTODWVOOK ACIYSIAASL AVFVVSFLPV
THH7
260
270
280
290
300
HLGFFLQFLV RNSFIVECRA KOSISFFLOL SMCFSNVNCC LDVFCYYFVI
H8
310
320
330
KEPRMNIRAH RPSRVOLVLO DTTISRGHHI HHH](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F44a49771-0216-48f8-b246-34968594d80b%2Ff354cd9f-f442-4372-ae17-c6e4d03b89e7%2Fz2logc_processed.png&w=3840&q=75)
Transcribed Image Text:TMH1
10
20
30
40
50
HDYRDDDAMS OONTSGDCLF DGVNELMKTL QFAVHIPTFV LGLLLNLLAI
TMH2
60
70
80
90
100
HGFSTFLKNR WPDYAATSIY MINLAVFDLL LVLSLPFKMV LSQVOSPFPS
TMH3
110
120
130
140
150
LCTLVECLYF VSMYGSVFTI CFISMDRFLA IRYPLLVSHL RSPRKIFGIC
TMH4
THH5
160
170
180
190
200
CTIWVLVWTG SIPIYSFHGK VEKYMCFHNM SDDTHSAKVE FPLEVFGFLL
THH6
210
220
230
240
250
PHGIMGFCCS RSIHILLGRR DHTODWVOOK ACIYSIAASL AVFVVSFLPV
THH7
260
270
280
290
300
HLGFFLQFLV RNSFIVECRA KOSISFFLOL SMCFSNVNCC LDVFCYYFVI
H8
310
320
330
KEPRMNIRAH RPSRVOLVLO DTTISRGHHI HHH
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