What is the commercial use of ibuprofen? 2. What are the important criteria of a good resolving agent in the resolution of ibuprofen? 3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Briefly answer the following Questions

1. What is the commercial use of ibuprofen?

2. What are the important criteria of a good resolving agent in the resolution of ibuprofen?

3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

H2SO4
NH3
OH
(S)-(+)-ibuprofen
(not water soluable)
(S,S) Salt
HSO4
NH3
ammonium salt
(water soluable)
Transcribed Image Text:H2SO4 NH3 OH (S)-(+)-ibuprofen (not water soluable) (S,S) Salt HSO4 NH3 ammonium salt (water soluable)
CH3
NH3
NH2
CH3
(S,S) Salt- Insoluable in Aqueous Solution
Forms Precipitate
+
OH
Racemic-(+)-Ibuprofen
(S)-(-)-methy lbenzyl amine
CHa
NH3
(R,S) Salt- Soluable in Aqueous Solution
Transcribed Image Text:CH3 NH3 NH2 CH3 (S,S) Salt- Insoluable in Aqueous Solution Forms Precipitate + OH Racemic-(+)-Ibuprofen (S)-(-)-methy lbenzyl amine CHa NH3 (R,S) Salt- Soluable in Aqueous Solution
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