Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
What is a simple way of making a knockout mouse in terms of DNA recombinant technology?
A knockout mouse, or knock-out mouse, is a genetically modified mouse in which researchers have inactivated some specific gene/s.
Knocking out is done by replacing the existing section of DNA or disrupting it with an artificial piece of DNA, so that the original protein is not expressed.
Example:
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