Thermochemistry
Thermochemistry can be considered as a branch of thermodynamics that deals with the connections between warmth, work, and various types of energy, formed because of different synthetic and actual cycles. Thermochemistry describes the energy changes that occur as a result of reactions or chemical changes in a substance.
Exergonic Reaction
The term exergonic is derived from the Greek word in which ‘ergon’ means work and exergonic means ‘work outside’. Exergonic reactions releases work energy. Exergonic reactions are different from exothermic reactions, the one that releases only heat energy during the course of the reaction. So, exothermic reaction is one type of exergonic reaction. Exergonic reaction releases work energy in different forms like heat, light or sound. For example, a glow stick releases light making that an exergonic reaction and not an exothermic reaction since no heat is released. Even endothermic reactions at very high temperature are exergonic.
![1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and S19
on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acids
form chains through a condensation reaction, as illustrated here:
https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemist
ry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation Reactions). Here are
those structures, from Wikipedia:
*Copy/paste the link into your browser*
Alanine
Serine
H3C.
`OH
но
ÑH2
NH2
Skeletal formula of L-
Skeletal formula of L-alanine
serine
Ball-and-stick model
Space-filling model
Ball-and-stick model
Space-filling model
The blue portions of the structure represent nitrogen atoms, and the red portions represent
oxygen. The same is true in Figures 1 and 2 in the paper. This interaction is noted to be new to
SARS-COV-2 compared to SARS-CoV and is a key finding in explaining how the behaviors of
these viruses differ. What kind of interactions could be occurring between A475 and S19? Mark
all that apply.
A. Dipole-dipole
B. London dispersion
C. lon-ion
D. Hydrogen bond](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F38a9992d-9c05-40da-9474-aaafff450dc4%2Feb24aefb-0b52-47df-a184-84154a3dee5f%2Fjqe6a9t_processed.jpeg&w=3840&q=75)
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