What information provided by Jamie would lead the physician to suspect a systemic disease? Include any environmental or lifestyle clues. 2. Def ne autoimmune disease and autoantibody. 3. What environmental triggers are associated with autoimmune diseases? 4
What information provided by Jamie would lead the physician to suspect a systemic disease? Include any environmental or lifestyle clues. 2. Def ne autoimmune disease and autoantibody. 3. What environmental triggers are associated with autoimmune diseases? 4
What information provided by Jamie would lead the physician to suspect a systemic disease? Include any environmental or lifestyle clues. 2. Def ne autoimmune disease and autoantibody. 3. What environmental triggers are associated with autoimmune diseases? 4
What information provided by Jamie would lead the physician to suspect a systemic disease? Include any environmental or lifestyle clues. 2. Def ne autoimmune disease and autoantibody. 3. What environmental triggers are associated with autoimmune diseases? 4. What are some of the autoimmune diseases? 5. What are the typical signs and symptoms of autoimmune diseases using lupus as an example? 6. Using WebMD (www.webmd.com) or MedlinePlus (www.nlm.nih.gov/medlineplus), fnd the criteria for the diagnosis of systemic lupus erythematous, rheumatoid arthritis, Lyme disease, and chronic Epstein Barr syndrome. 7. Why does the doctor suspect that Jamie may be anemic?
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Alisa J. Petree, Medical Laboratory Technician Program
Sondra A. Dubowsky, Biology Department
Mary A. Sides, Biology Department
McLennan Community College, Waco, TX
Partl- The Investigative Process
Jamie is a 26-year-old graduate student at the University of Arkansas-Monticello. She is working on her PhD in
biology. As a biologist, she enjoys spending time outdoors when she can. The campus is on the edge of the woods and
it is a nice place for Jamie to walk and relax to relieve the stress of graduate school. Jamie has not been able to enjoy
her walks lately due to the fatigue she has been experiencing. Others have noticed that she does not have the stamina
she had in the past to complete her research.
Her major professor convinces her that it would be a good idea to make an appointment to see her family physician
to determine the source of her fatigue. He suggests that maybe she has a viral infection, and she just needs to get some
rest. She is able to get an appointment with her family practitioner. When she arrives at the clinic, the nurse takes her
blood pressure and temperature. Her blood pressure is 128/74 and her temperature is a slightly elevated 101.2°F.
She is asked to provide her family medical history and to describe any symptoms she has noticed. Jamie tells her
doctor that her maternal grandmother had rheumatism and was not able to get around. Her father had prostate cancer.
She cannot think of any other family illnesses. She tells her doctor that in addition to feeling run down, her knees
and elbows have been aching, and she has been having trouble pipetting because of pain in her hands. She has been
experiencing frequent cold sores that she has been treating with over-the-counter medication. She attributes her recent
weight loss to poor eating habits as a student. On general examination, the doctor finds a rash on her upper back
where she is typically exposed to the sun and swollen lymph nodes on her neck.
The doctor decides that further tests are required to rule out some obvious possibilities. He suspects an autoimmune
disease such as lupus (systemic lupus erythematous, SLE) or rheumatoid arthritis (RA), a tick born disease like Lyme
disease, anemia, or chronic Epstein Barr virus syndrome. Jamie is sent to the lab where blood is drawn. She is asked to
return the following week to review the lab test results.
Questions
1. What information provided by Jamie would lead the physician to suspect a systemic disease? Include any
environmental or lifestyle clues.
2. Define autoimmune disease and autoantibody.
3. What environmental triggers are associated with autoimmune diseases?
II
Expert Solution
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