What enzyme will not be used if the oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? a) Transaldolase b) Ribulose 5-phosphate isomerase
What enzyme will not be used if the oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? a) Transaldolase b) Ribulose 5-phosphate isomerase
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
What enzyme will not be used if the oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate?
a) Transaldolase
b) Ribulose 5-phosphate isomerase
Expert Solution
Step 1
Pentose phosphate pathway:
- The pentose phosphate pathway is an alternative pathway for the metabolism of glucose.
- It is a more complex pathway than glycolysis and is also known as hexose monophosphate shunt (HMP).
- It occurs in cytosol and oxidation occurs by dehydrogenation using NADP+ and not NAD+.
- The pathway provides a major portion of the cell's NADPH, which function as a biochemical reductant.
- It also produces ribose phosphate that is required for the biosynthesis of nucleotides.
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