wenty-two young asthmatic volunteers were studied to assess the short-term effects of sulfur dioxide (SO2) exposure under various conditions [12]. The baseline data in Table 12.30 were presented regarding bronchial reactivity to SO2 stratified by lung function (as defined by forced expiratory volume / forced vital capacity [FEV1/FVC]) at screening. *12.6 Test the hypothesis that there is an overall mean difference in bronchial reactivity among the three lung-function groups. *12.7 Compare the means of each pair of groups using the LSD method. *12.8 Compare the means of each pair of groups using the Bonferroni method.

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Twenty-two young asthmatic volunteers were studied to assess the short-term effects of sulfur dioxide (SO2) exposure under various conditions [12]. The baseline data in Table 12.30 were presented regarding bronchial reactivity to SO2 stratified by lung function (as defined by forced expiratory volume / forced vital capacity [FEV1/FVC]) at screening. *12.6 Test the hypothesis that there is an overall mean difference in bronchial reactivity among the three lung-function groups. *12.7 Compare the means of each pair of groups using the LSD method. *12.8 Compare the means of each pair of groups using the Bonferroni method.

TABLE 12.30 Relationship of bronchial reactivity
to So, (cm H,0/s) grouped by lung
function at screening among
22 asthmatic volunteers
Lung-function group
Group A
FEV,/FVC
S74%
Group B
FEV,/FVC
75-84%
Group C
FEV,FVC
2 85%
20.8
7.5
9.2
4.1
7.5
2.0
30.0
11.9
2.5
24.7
4.5
6.1
13.8
3.1
7.5
8.0
4.7
28.1
10.3
10.0
5.1
2.2
Source: Based on the American Review of Respiratory Disease, 131(2),
221-225, 1985.
Transcribed Image Text:TABLE 12.30 Relationship of bronchial reactivity to So, (cm H,0/s) grouped by lung function at screening among 22 asthmatic volunteers Lung-function group Group A FEV,/FVC S74% Group B FEV,/FVC 75-84% Group C FEV,FVC 2 85% 20.8 7.5 9.2 4.1 7.5 2.0 30.0 11.9 2.5 24.7 4.5 6.1 13.8 3.1 7.5 8.0 4.7 28.1 10.3 10.0 5.1 2.2 Source: Based on the American Review of Respiratory Disease, 131(2), 221-225, 1985.
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