VI ADP ATP II ADP ADP II IV ADP (P Reference: Ref 20-2 In the figure, which panel represents the transient rigor state? Select one: O a VI O b. IV Ос. V O d. I
VI ADP ATP II ADP ADP II IV ADP (P Reference: Ref 20-2 In the figure, which panel represents the transient rigor state? Select one: O a VI O b. IV Ос. V O d. I
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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Transcribed Image Text:**Muscle Contraction Cycle Diagram**
The figure illustrates a sequence of events in the muscle contraction cycle, demonstrating the interaction between actin and myosin filaments. The cycle is divided into six panels labeled I through VI, with arrows indicating the progression of each step.
1. **Panel I**: A myosin head is bound to actin with no nucleotides attached, suggesting the rigor state.
2. **Panel II**: ATP binds to the myosin head, causing a conformational change and the release of myosin from actin.
3. **Panel III**: The myosin head is detached from the actin filament, and the ATP is hydrolyzed to ADP and inorganic phosphate (Pi).
4. **Panel IV**: With ADP and Pi still bound, the myosin head is cocked and reattaches weakly to a new position on the actin filament.
5. **Panel V**: The release of Pi initiates the power stroke, pulling the actin filament.
6. **Panel VI**: After the power stroke, ADP is released, and the myosin head is again in a state ready to bind ATP.
**Question:**
In the figure, which panel represents the transient rigor state?
**Options:**
- a. VI
- b. IV
- c. V
- d. I
**Answer:**
Panel I represents the transient rigor state, where the myosin head is tightly bound to the actin filament without any nucleotides.
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