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Using the information, deduce why and how catalase activity is regulated inside the liver cells.

Using the information, deduce why and how catalase activity is regulated inside the liver cells.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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)Using the information, deduce why and how catalase activity is regulated inside the liver cells.
Transcribed Image Text:)Using the information, deduce why and how catalase activity is regulated inside the liver cells.
Created in ExamBuilder 42 Liver cells have a high metabolic rate. Hydrogen peroxide is a metabolic product produced in significant quantities in liver cells. It needs to be removed in order to prevent serious damage to the liver cells. Hydrogen peroxide is detoxified by the enzyme catalase: 2H,O, O 2H,0 +0, Catalase has a very high turnover number. A single catalase molecule can catalyse the breakdown of approximately 6 million hydrogen peroxide molecules every minute. Catalase is found in peroxisomes inside th liver cells. Peroxisomes are organelles surrounded by a single membrane. The activity of catalase was investigated in a laboratory, using chopped liver tissue and dilute hydrogen peroxide. When the chopped liver was added to the hydrogen peroxide large quantities of froth as bubbles of oxygen were produced in the liquid. Fig. 17.3 shows the effect of increasing enzyme concentration on the rate of the reaction.
Transcribed Image Text:Created in ExamBuilder 42 Liver cells have a high metabolic rate. Hydrogen peroxide is a metabolic product produced in significant quantities in liver cells. It needs to be removed in order to prevent serious damage to the liver cells. Hydrogen peroxide is detoxified by the enzyme catalase: 2H,O, O 2H,0 +0, Catalase has a very high turnover number. A single catalase molecule can catalyse the breakdown of approximately 6 million hydrogen peroxide molecules every minute. Catalase is found in peroxisomes inside th liver cells. Peroxisomes are organelles surrounded by a single membrane. The activity of catalase was investigated in a laboratory, using chopped liver tissue and dilute hydrogen peroxide. When the chopped liver was added to the hydrogen peroxide large quantities of froth as bubbles of oxygen were produced in the liquid. Fig. 17.3 shows the effect of increasing enzyme concentration on the rate of the reaction.
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