Using table C1 given to you in the coursework instructions, which ONE of the following would Proteus mirabilis be considered resistant to if the zone size was 20 mm?   Select one: A. Ciprofloxacin B. Co-amoxiclav C. Mecillinam D. Fosfomycin E. Nalidixic acid

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Using table C1 given to you in the coursework instructions, which ONE of the following would Proteus mirabilis be considered resistant to if the zone size was 20 mm?


 

Select one:
A.

Ciprofloxacin

B.

Co-amoxiclav

C.

Mecillinam

D.

Fosfomycin

E.

Nalidixic acid

Table C1: Interpretative values for disc susceptibility evaluation of coliforms, E. coli and Proteus mirabilis to antimicrobials
commonly used to treat urinary tract infections
Antibiotic
Amoxicillin
Ampicillin
Cephalexin
Ciprofloxacin
Co-amoxiclave
Fosfomycing.h
Mecillinam
Nalidixic acid
Nitrofurantoin
Norfloxacin
Trimethoprim
MIC BP (mg/L)
R>
32
32
32
4
32
128
8
16
32
4
2
S≤
32
32
32
4
32
128
8
16
32
4
2
Disc content
(µg)
25
25
30
1
20/10
200/50
10
30
200
2
2.5
R<
11
11
-
19
11
17
15
16
Coliforms
I
-
-
Interpretation of zone diameters (mm)
E. coli
2_12 12-20 12--18-16 17
Sz
R≤
11
11
15
19
11
19
13
17
19
15
16
Sz R≤
12 12 16 20 12 20 14 18 20 16 17
11
11
11
19
11
33
14 13
18 17
15
16
Pr. mirabilis
|
212 12 12 20 12 34 14 18-16 17
Sz
Transcribed Image Text:Table C1: Interpretative values for disc susceptibility evaluation of coliforms, E. coli and Proteus mirabilis to antimicrobials commonly used to treat urinary tract infections Antibiotic Amoxicillin Ampicillin Cephalexin Ciprofloxacin Co-amoxiclave Fosfomycing.h Mecillinam Nalidixic acid Nitrofurantoin Norfloxacin Trimethoprim MIC BP (mg/L) R> 32 32 32 4 32 128 8 16 32 4 2 S≤ 32 32 32 4 32 128 8 16 32 4 2 Disc content (µg) 25 25 30 1 20/10 200/50 10 30 200 2 2.5 R< 11 11 - 19 11 17 15 16 Coliforms I - - Interpretation of zone diameters (mm) E. coli 2_12 12-20 12--18-16 17 Sz R≤ 11 11 15 19 11 19 13 17 19 15 16 Sz R≤ 12 12 16 20 12 20 14 18 20 16 17 11 11 11 19 11 33 14 13 18 17 15 16 Pr. mirabilis | 212 12 12 20 12 34 14 18-16 17 Sz
Expert Solution
Step 1

Proteus mirabilis is resistant towards Ciprofloxacin if a zone of inhibition is formed at 20mm. Thus the correct answer is option A. Ciprofloxacin. The antibiotic working concentration is 1μg for the bacterial colonies.

 

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