Using Ethylene, C2H4, and methyl bromide, CH3Br, as your sole sources of carbon, propose a synthesis for t-BuOH, (CH3)3COH. *the synthesis should take about 7 steps and will include an alkylation and a Grignard reaction. Use one equivalent of methyl bromide for the alkylation step and use the second one to make the Grignard reagent. The substrate in the Grignard reaction will be a carbonyl - make this from your alkyne AFTER alkylation. *show all reactants and intermediates H +2 H H Br -7 steps H₂C H₂C OH CH3

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Using Ethylene, C2H4, and methyl bromide, CH3Br, as your sole sources of carbon, propose a
synthesis for t-BuOH, (CH3)3COH.
*the synthesis should take about 7 steps and will include an alkylation and a Grignard reaction. Use
one equivalent of methyl bromide for the alkylation step and use the second one to make the
Grignard reagent. The substrate in the Grignard reaction will be a carbonyl - make this from your
alkyne AFTER alkylation.
*show all reactants and intermediates
H
+2
H
H
Br
-7 steps
H₂C
H₂C
OH
CH3
Transcribed Image Text:Using Ethylene, C2H4, and methyl bromide, CH3Br, as your sole sources of carbon, propose a synthesis for t-BuOH, (CH3)3COH. *the synthesis should take about 7 steps and will include an alkylation and a Grignard reaction. Use one equivalent of methyl bromide for the alkylation step and use the second one to make the Grignard reagent. The substrate in the Grignard reaction will be a carbonyl - make this from your alkyne AFTER alkylation. *show all reactants and intermediates H +2 H H Br -7 steps H₂C H₂C OH CH3
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