Use what you know about the physiology of neurons to answer the following questions. Treat questions a - c as unrelated to each other. a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this brings the neuron closer to or further from its threshold potential. b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question
Use what you know about the physiology of neurons to answer the following questions. Treat
questions a- c as unrelated to each other.
a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate
effect on the resting potential: identify which ions diffuse across the membrane, which direction
they diffuse (and why), and whether this brings the neuron closer to or further from its
threshold potential.
b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate
effect on the resting potential: identify which ions diffuse across the membrane, which
direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron.
c. Imagine that in a different neuron, voltage-gated K" channels open quickly, only 0.3ms after
voltage-gated Na channels. Predict changes in timing, amplitude and shape of an AP by drawing
one labeled diagram comparing a normal AP (solid line) to your AP (dashed line), and explaining
why these changes occur. Label the axes, depolarization and repolarization phases, and
threshold potential.
Transcribed Image Text:Use what you know about the physiology of neurons to answer the following questions. Treat questions a- c as unrelated to each other. a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this brings the neuron closer to or further from its threshold potential. b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron. c. Imagine that in a different neuron, voltage-gated K" channels open quickly, only 0.3ms after voltage-gated Na channels. Predict changes in timing, amplitude and shape of an AP by drawing one labeled diagram comparing a normal AP (solid line) to your AP (dashed line), and explaining why these changes occur. Label the axes, depolarization and repolarization phases, and threshold potential.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Anatomy and Physiology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Anatomy & Physiology
Anatomy & Physiology
Anatomy and Physiology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy
Human Anatomy
Anatomy and Physiology
ISBN:
9780135168059
Author:
Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher:
Pearson Education, Inc.,
Anatomy & Physiology: An Integrative Approach
Anatomy & Physiology: An Integrative Approach
Anatomy and Physiology
ISBN:
9780078024283
Author:
Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher:
McGraw-Hill Education
Human Anatomy & Physiology (Marieb, Human Anatomy…
Human Anatomy & Physiology (Marieb, Human Anatomy…
Anatomy and Physiology
ISBN:
9780321927040
Author:
Elaine N. Marieb, Katja Hoehn
Publisher:
PEARSON