Use what you know about the physiology of neurons to answer the following questions. Treat questions a - c as unrelated to each other. a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this brings the neuron closer to or further from its threshold potential. b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron.
Use what you know about the physiology of neurons to answer the following questions. Treat questions a - c as unrelated to each other. a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this brings the neuron closer to or further from its threshold potential. b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate effect on the resting potential: identify which ions diffuse across the membrane, which direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:Use what you know about the physiology of neurons to answer the following questions. Treat
questions a- c as unrelated to each other.
a. Imagine that a toxin creates pores in a neuron that are permeable to Na*. Describe its immediate
effect on the resting potential: identify which ions diffuse across the membrane, which direction
they diffuse (and why), and whether this brings the neuron closer to or further from its
threshold potential.
b. Imagine that a toxin makes K* leak channels more permeable to K* ions. Describe its immediate
effect on the resting potential: identify which ions diffuse across the membrane, which
direction they diffuse (and why), and whether this depolarizes or hyperpolarizes the neuron.
c. Imagine that in a different neuron, voltage-gated K" channels open quickly, only 0.3ms after
voltage-gated Na channels. Predict changes in timing, amplitude and shape of an AP by drawing
one labeled diagram comparing a normal AP (solid line) to your AP (dashed line), and explaining
why these changes occur. Label the axes, depolarization and repolarization phases, and
threshold potential.
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