Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
UDP , gemcitabine was shown to undergo two successive phosphorylations at . The product, gemcitabine Like cytidine -diphosphate, is an analog of |, a substrate for ribonucleotide reductase. However, gemcitabine diphosphate is a inhibitor potent of ribonucleotide reductase, so it DNA replication by stimulator depriving the replisome of dNTPs. inhibits activates C-5' C-3' C-3' and C-5' 3' 5' 3', 5' uridine adenosine CDP ADP

UDP , gemcitabine was shown to undergo two successive phosphorylations at . The product, gemcitabine Like cytidine -diphosphate, is an analog of |, a substrate for ribonucleotide reductase. However, gemcitabine diphosphate is a inhibitor potent of ribonucleotide reductase, so it DNA replication by stimulator depriving the replisome of dNTPs. inhibits activates C-5' C-3' C-3' and C-5' 3' 5' 3', 5' uridine adenosine CDP ADP

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
100%
Solve it asap
Speculate on the pathway for activation and the identity of the target enzyme. Match the words in the left column to the appropriate blanks in the sentences on the right. Reset Help UDP Like , gemcitabine was shown to undergo two successive phosphorylations at cytidine The product, gemcitabine -diphosphate, is an analog of inhibitor ,a substrate for ribonucleotide reductase. However, gemcitabine diphosphate is a potent of ribonucleotide reductase, so it DNA replication by stimulator depriving the replisome of dNTPs. inhibits activates С-5 C-3' C-3' and C-5' 3' 5' 3', 5' uridine adenosine CDP ADP
Transcribed Image Text:Speculate on the pathway for activation and the identity of the target enzyme. Match the words in the left column to the appropriate blanks in the sentences on the right. Reset Help UDP Like , gemcitabine was shown to undergo two successive phosphorylations at cytidine The product, gemcitabine -diphosphate, is an analog of inhibitor ,a substrate for ribonucleotide reductase. However, gemcitabine diphosphate is a potent of ribonucleotide reductase, so it DNA replication by stimulator depriving the replisome of dNTPs. inhibits activates С-5 C-3' C-3' and C-5' 3' 5' 3', 5' uridine adenosine CDP ADP
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS