TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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TRUE OR FALSE
1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases
2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form
3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
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