TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter31: Completing The Protein Life Cycle: Folding, Processing, And Degradation
Section: Chapter Questions
Problem 15P
Related questions
Question
TRUE OR FALSE
1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases
2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form
3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated
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