ch of these heterocycli drugs is likely to be the least soluble in water? Use parameter to decide. Tramadol Chemical Formula: C16H25NO2 NH YOUR Ou Pantoprazole Torasemide Chemical Formula: C16H20403S Chemical Formula: C16H15F2N₂O4S Temazepam Chemical Formula: C16H13CIN₂02 Tioconazole Chemical Formula: C16H13jN₂ Fspº A. Tramadol B. Pantoprazole C. Torasemide D. Temazepam E. Toconazole

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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Question
Which of these heterocyclic drugs is likely to be the least soluble in water? Use the Fsp³
parameter to decide.
OH
Tramadol
Chemical Formula:
C16H25NO2
YOUR OW
Pantoprazole
Torasemide
Chemical Formula:
C16H15F2N3O4S
Chemical Formula:
C16H20N4O3S
Temazepam
-OH
Chemical Formula:
C16H13CIN₂O2
Tioconazole
Chemical Formula:
C16H13C3N₂OS
A. Tramadol
B. Pantoprazole
C. Torasemide
D. Temazepam
E. Toconazole
Transcribed Image Text:Which of these heterocyclic drugs is likely to be the least soluble in water? Use the Fsp³ parameter to decide. OH Tramadol Chemical Formula: C16H25NO2 YOUR OW Pantoprazole Torasemide Chemical Formula: C16H15F2N3O4S Chemical Formula: C16H20N4O3S Temazepam -OH Chemical Formula: C16H13CIN₂O2 Tioconazole Chemical Formula: C16H13C3N₂OS A. Tramadol B. Pantoprazole C. Torasemide D. Temazepam E. Toconazole
Expert Solution
Step 1: Determining Water Solubility Based on fsp3 Parameter

To assess the water solubility of heterocyclic drugs, we can use the fsp3 parameter. This parameter indicates the fraction of sp3-hybridized carbon atoms in a compound, with lower values suggesting lower water solubility.

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