Treatment with methotrexate blocks the folate pathway and causes defects during embryogenesis in vertebrates. In humans, a lack of folate during pregnancy can lead to development of neural tube defects. In zebrafish development, methotrexate blocks embryo development at the stage of early somite formation. Which of the following events would also be blocked by methotrexate treatment of zebrafish embryos if development stops early in the stage of somite formation? Choose one or more: O A. internalization of yolk into the developing gut cavity O B. epiboly O C. eye development O D. movement of cells of external layer into the interior to eventually form the gut cavity

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Treatment with methotrexate blocks the folate pathway and causes defects during embryogenesis in vertebrates. In humans, a lack of
folate during pregnancy can lead to development of neural tube defects. In zebrafish development, methotrexate blocks embryo
development at the stage of early somite formation. Which of the following events would also be blocked by methotrexate treatment of
zebrafish embryos if development stops early in the stage of somite formation?
Choose one or more:
O A. internalization of yolk into the developing gut cavity
O B. epiboly
O C. eye development
O D. movement of cells of external layer into the interior to eventually form the gut cavity
Transcribed Image Text:Treatment with methotrexate blocks the folate pathway and causes defects during embryogenesis in vertebrates. In humans, a lack of folate during pregnancy can lead to development of neural tube defects. In zebrafish development, methotrexate blocks embryo development at the stage of early somite formation. Which of the following events would also be blocked by methotrexate treatment of zebrafish embryos if development stops early in the stage of somite formation? Choose one or more: O A. internalization of yolk into the developing gut cavity O B. epiboly O C. eye development O D. movement of cells of external layer into the interior to eventually form the gut cavity
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