Transactivation domain Repressor protein protein Activator proteln Coactivator TEIID (enhanced) Coding sequenco (sllenced) Coding soquence TEID Enhancer Core promoter Silencer promoter The activator/coactivator complex recrults TFID to the core promoter and/or activates Its function. Transcription will be enhanced. The repressor proteln Inhibits the binding of TFIID to the core promoter or Inhibits Its function. Transcription Is silenced. (a) Transcriptional activation via TFIID (b) Transcriptional reprossion vla TFIID

Q: For each of the following transcription factors, explain how eukaryotic transcriptional initiation…

A: A transcription factor is a sequence specific DNA-binding factor and upon binding to the DNA…

Q: What could be the effect  of a base substitution which prevents post-transcriptional removal of an…

A: A base substitution is a genetic mutation where a single nucleotide base is changed in the sequence…

Q: If some cell-surface receptors, including Notch, can rapidly signal to the nucleus by activating…

A: The biological cells are a hub of metabolic activities. These cells interact among themselves to…

Q: What is the major difference between transcriptional regulationin Archaea and eukaryotes?

A: Prokaryotes are the single cellular organism in which their nucleus is not confined and the absence…

Q: How would a mutation which prevented Gal3 from binding to Gal80 affect gene expression from the GAL…

A: Galactose metabolizing genes express themselves in the presence of galactose. Galactose is…

Q: Explain using leucine zipper motifs as an example, how protein-protein interactions between…

A: DNA is the genetic information that a cell obtains from its parents. DNA contains a specific…

Q: What critical roles does the TFIIH CTD kinase play in regulating the switch from a pre-initiation…

A: Hi, Thanks For Your Question.  Answer : TFIIH Is Required For The Beginning And Transition To…

Q: What is the purpose of CAP and CAMP in gene regulation?

A: A wide range of mechanism carried out by the cells that act to induce or repress the synthesis of…

Q: If the two trp codons in the leader sequence were mutated to stop codons, what effect would it have…

A: DNA is the preferred carrier of genetic information in most living organisms except for certain RA…

Q: If a repressor prevents TFIID from binding to the TATA box, why does this inhibit transcription?

A: TFIID - It is an important transcription factor, which plays a key role in the activity of RNA…

Q: which of the following correctly describes how protein kinase A can activate genes? A: nuclear…

A: By activating cAMP-dependent protein kinase-A (PK-A), which is activated when cAMP binds to the…

Q: why the repressor proteins bind with the major groove in the DNA helix?

A: DNA is a double helical structure as described by Watson and crick consisting of two loops that is…

Q: If a gene is repressible and under positive control, what kind of effector molecule and regulatory…

A: Gene regulation vary in prokaryotes and eukaryotes. Prokaryotic genes regulation may administrated…

Q: What is the relationship between promoters, regulatory DNA sequences, and transcription regulators?…

A: Gene expression is regulated by the binding of of different proteins on different regions of DNA.

Q: Why is it said that transcriptional regulation in eukaryotes is characterized by combinatorial…

A: The cells are the primary unit of life. Based on the number of cells an organism may be prokaryotic…

Q: Which RNA conformation favors transcription—the form with the antiterminator stem-loop or the form…

A: The process of transcription allows the formation of RNA from DNA with help of DNA-dependent RNA…

Q: Some mutations in the trp 5′ UTR increase termination by the attenuator. Where might these mutations…

A: Tryptophan operon consists of a leader region located at the 5' terminal of mRNA called 5' UTR. The…

Q: How do draw the sequence in this question? Draw the sequence of molecular events that occurs to…

A: STAT (signal transducer and activator of transcription) protein family are transcription factors…

Q: Which molecules act as co-repressor for pur respressor in prokaryotes?

A: Co repressor- It's a substance which inhibits the gene expression.A co repressor downregulates the…

Q: You identify a new transcriptional regulator that binds a known sequence of DNA. You are able to…

A: Identify a new transcriptional regulator that binds a known sequence of DNA.Observe the behavior of…

Q: A researcher was studying a new transcription regulator called UOT and wanted to study its…

A: Green fluorescent (GFP) protein is considered as the marker protein, which helps to attach the…

Q: How could the increase in a protein that inhibits the activity of sigma-32 lead to an increase in…

A: The "molecular chaperone", dnaK, is induced upon heat shock and promotes ATP-dependent refolding or…

Q: What are the major differences between a repressor protein anda riboswitch in the control of gene…

A: The riboswitch acts as a regulatory mechanism of translation process, which resembles as an…

Q: According to the Jacob-Monod model of regulation of gene transcription in bacteria, the DNA sequence…

A: Q.Explanation:- Lac operon is a concept that controls the transcription in prokaryotic cells such as…

Q: Why is the trp attenuation mechanism unique to prokaryotes?

A: Attenuation is a control mechanism that operates to regulate the expression of genes of an operon.…

Q: Some compounds called antiinducers bind to repressors such as the lac repressor and inhibit the…

A: Operon is a genetic regulatory system that is mainly found in bacteria and viruses. In this system,…

Q: What analogies can you draw between transcriptionaltrans-acting factors that activate gene…

A: Introduction Bacteria are common, largely free-living organisms that are often made up of only one…

Q: At 2:00 pm, you measured intracellular arginine at 100M. After addition of 200M of arginine to the…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: How would a mutation in E. coli make the lac operator unable to bind the active repressor to affect…

A: Numerous factors may result in mutations. Certain mutations appear to occur naturally, with no…

Q: Explain how a regulatory transcription factor exerts its effects via TFIID or mediator.

A: Transcription is a process in which the nucleotide sequences of a gene are transcribed into the mRNA…

Q: Why is an NFR needed at the core promoter for transcription to occur?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Many transcriptional activators are proteins with a DNA-binding domain (DBD) and an activation…

A: Introduction  Protein is the key biomolecule in the biological system, any important physiological…

Q: Explain the function(s) of each of the basal transcription factors (the TFII "alphabet soup")

A: Basal transcription factors are required for the initiation of the transcription or mRNA synthesis.…

Q: What is an example of a post transcriptional regulation?Keep it short and simple

A: Post-transcriptional regulation encompasses various processes that occur after mRNA synthesis,…

Q: What would be the effect on transcription if a mutation occurred in the gene that encodes GAL3, so…

A: Transcription is a very significant level of gene expression control in eukaryotes and needs various…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.