Time to recurrence of brain metastasis was evaluated on 48 patients. 23 of the patients received treatment with radiotherapy alone and 25 patients received surgery to remove the tumor followed by radiotherapy. You are given the SAS output below to evaluate the 2 different treatments. The variable combo = 1 if the patient received both surgery and radiotherapy and combo = 0 if the patient received radiotherapy alone. ( See images uploaded for SAS output and survival curves)    a. Which treatment to do you prefer? Use an appropriate hypothesis test (following all of the steps) to support your decision. b. Suppose you are told that the 95% confidence interval for the HR comparing treatment with radiotherapy + surgery to treatment with radiotherapy alone is (0.54, 1.32). Do you think this is reasonable? Why or why not?

MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
icon
Related questions
Question

Time to recurrence of brain metastasis was evaluated on 48 patients. 23 of the patients received treatment with radiotherapy alone and 25 patients received surgery to remove the tumor followed by radiotherapy. You are given the SAS output below to evaluate the 2 different treatments. The variable combo = 1 if the patient received both surgery and
radiotherapy and combo = 0 if the patient received radiotherapy alone.

( See images uploaded for SAS output and survival curves) 

 

a. Which treatment to do you prefer? Use an appropriate hypothesis test (following all of the steps) to support your decision.
b. Suppose you are told that the 95% confidence interval for the HR comparing treatment with radiotherapy + surgery to treatment with radiotherapy alone is (0.54, 1.32). Do you think this is reasonable? Why or why not?

 

Test of Equality over Strata
Pr >
Test
Chi-Square
DF
Chi-Square
Log-Rank
15.7833
1
<.0001
Wilcoxon
15.6843
1
<.0001
-2Log(LR)
9.1845
1
0.0024
Transcribed Image Text:Test of Equality over Strata Pr > Test Chi-Square DF Chi-Square Log-Rank 15.7833 1 <.0001 Wilcoxon 15.6843 1 <.0001 -2Log(LR) 9.1845 1 0.0024
Product-Limit Survival Estimates
1.0
+ Censored
0.8
0.6
++H +
0.4
0.2
0.0
50
100
150
200
time
combo
1
Survival Probability
Transcribed Image Text:Product-Limit Survival Estimates 1.0 + Censored 0.8 0.6 ++H + 0.4 0.2 0.0 50 100 150 200 time combo 1 Survival Probability
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc
Probability and Statistics for Engineering and th…
Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning
Statistics for The Behavioral Sciences (MindTap C…
Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning
Elementary Statistics: Picturing the World (7th E…
Elementary Statistics: Picturing the World (7th E…
Statistics
ISBN:
9780134683416
Author:
Ron Larson, Betsy Farber
Publisher:
PEARSON
The Basic Practice of Statistics
The Basic Practice of Statistics
Statistics
ISBN:
9781319042578
Author:
David S. Moore, William I. Notz, Michael A. Fligner
Publisher:
W. H. Freeman
Introduction to the Practice of Statistics
Introduction to the Practice of Statistics
Statistics
ISBN:
9781319013387
Author:
David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:
W. H. Freeman