Think of reasons why it is important to maintain the number and structure of chromosomes

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Chapter15: Obstetric And Gynecologic Surgery
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Observation 1: 1 out of 2 first trimester abortuses show abnormal karyotypes with 96% caused by numerical abnormalities and 4% with structural abnormalities. At live birth, 1 out of 160 has abnormal karyotypes with 60% caused by numerical changes. This number increases with fetuses of mothers over 35 years old to 1/50 for total incidence and 85% for numerical changes.

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  • Think of reasons why it is important to maintain the number and structure of chromosomes.
  • Why is maternal age so important?
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