The first thing that happens when O2 binds to Hemoglobin (Hb) is that: a Hb shifts to the Relaxed state. b Tension on Heme causes a hydrogen bond to break. c The pH of the bloodstream increases. d BPG binding increases.

The first thing that happens when O2 binds to Hemoglobin (Hb) is that: a Hb shifts to the Relaxed state. b Tension on Heme causes a hydrogen bond to break. c The pH of the bloodstream increases. d BPG binding increases.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

. Nicotine, one of the components of cigarettes, slows cilia" lining the respiratory tract, causes blood vessels to constrict, and increases heart rate. Another component of cigarette smoke is carbon monoxide. As you have read, carbon monoxide competes with oxygen for binding sites on the hemoglobin molecule found in red blood cells. Analyse the data presented, and describe the potential dangers associated with smoking.
1. Is this statement correct or incorrect? Explain. During strenuous exercise, the oxygen-hemoglobin dissociation curve shifts to the right. This rightward shift reflects an increase in the affinity of hemoglobin for oxygen and favors loading of O2 onto hemoglobin in the lungs. 2. Is this statement correct or incorrect? Explain. Compared to hemoglobin, myoglobin has a lower binding affinity for O2 and a higher O2 binding capacity, two characteristics that allow myoglobin to efficiently provide skeletal muscle cells with a readily-accessible reservoir of O2.
Most of the CO2 is transported through the bloodstream as…
In sickle cell disease: O poor oxygen binding causes deformation of red blood cells a mutation in the B-chain of hemoglobin causes hemoglobin to polymerize into fibres that distort red blood cells. O the oxygen binding curve of hemoglobin must be shifted to the left hemoglobin is no longer able to bind oxygen myoglobin is not longer able to bind BPG.
Each of the following statements briefly describes one of Hb an allosteric interactions. Which of the statements below are false? A drop in the [H+] of blood plasma would lead to a decrease Hb affinity for O₂. An increase in the partial pressure of CO₂ in the tissues would lead to a decrease Hb affinity for O₂- If you inhaled CO for an extended period of time, at partial pressures 1000 fold higher than normal indoor atmospheric pressure, your body would have a difficult time delivering oxygen to your tissues. When the partial pressure of oxygen is low within the atmosphere, your body responds by increasing the biological activity of Hb's negative effectors.
O2 bound to hemoglobin: a. acts the same as physically dissolved oxygen b. Comes off the hemoglobin (dissociates) more easily as you increase the oxygen partial pressure c. exerts a partial pressure d. Comes off the hemoglobin (dissociates) more easily as you increase the acidity (decrease the pH) e. all the options are correct 2. Air convection in mammals is driven by a smaller pressure gradient than blood convection because: a. Bronchioles have a greater resistance to flow than arterioles b. bronchioles tend to have a smaller radius than arterioles and capillaries c. air is easier to move with pressure gradients than blood d. air generally travels farther in your body than does blood e. air is heavier than blood 3. The rate of diffusion of gases is NOT determined by which of the following? a. The area of the surface across which diffusion is occurring b. The mechanical energy…
On 26 January 2014 the BBC reported that nineteen workers suffered carbon monoxide poisoning while working overnight in the Channel Tunnel. Upon reaching the hospital’s emergency room, pure oxygen was administered. In the context of the structure and function of red blood cells, EXPLAIN why this action was essential.
You are told that one teenager in a room with nine healthy teenagers of the same age, weight, etc is suffering from a genetic disease resulting in a low (but not zero) level of complex 1 of the respiratory chain. Since you must hurry to catch a plane for a medical conference, you only have 40 minutes to determine which of the ten persons has the deficiency of complex 1. Therefore you…. Have everyone hold their breath as long as possible and observe what happens. Have everyone drink two beers and observe what happens Have everyone go to asleep and observe what happens Have everyone run around the block as fast as possible and observe what happens
In the absence of 2,3-bisphosphoglycerate, the binding of oxygen by hemoglobin: a. is characterized by cooperativity b. resembles that of myoglobin c. binds at the end of the hemoglobin molecule d. is stabilized as the deoxy conformation of hemoglobin for the release into capillaries
Carbon monoxide (CO) is a colorless, odorless gas produced during combustion of fuels (for example, by car engines and furnaces). The following graph depicts an oxygen dissociation curve in the absence and presence of varying amounts of carbon monoxide. Based on these results, in the presence of 20% CO, when PO2 is 90mmHg you should expect each hemoglobin molecule to have _____ molecule(s) of O2 bound a) 1 b) 2 c) 3 d) 4