The word “isosteric” means having the same general three-dimensional shape. a. Look up amino acid structures. Find an amino acid side chain that is isosteric with a valine side chain. (Hint: hydrogen atoms are small, so while they of course affect molecular geometry, what matters more is the molecular geometry of non-hydrogen atoms connected to other non-hydrogen atoms.) Draw both side chains and label the molecular geometry around each non-hydrogen atom
The word “isosteric” means having the same general three-dimensional shape. a. Look up amino acid structures. Find an amino acid side chain that is isosteric with a valine side chain. (Hint: hydrogen atoms are small, so while they of course affect molecular geometry, what matters more is the molecular geometry of non-hydrogen atoms connected to other non-hydrogen atoms.) Draw both side chains and label the molecular geometry around each non-hydrogen atom
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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The word “isosteric” means having the same general three-dimensional shape.
a. Look up amino acid structures. Find an amino acid side chain that is isosteric with a valine side chain. (Hint: hydrogen atoms are small, so while they of course affect molecular geometry, what matters more is the molecular geometry of non-hydrogen atoms connected to other non-hydrogen atoms.) Draw both side chains and label the molecular geometry around each non-hydrogen atom.

Transcribed Image Text:H.
CH3
H3N
co2
co
H3N
co
co
Alanine
Valine
Leucine
Glycine
Gly, G
Ala, A
Val, V
Leu, L
H
HO.
co
co
co
co
Phenylalanine
Phe, F
Tyrosine
Туг, Y
Tryptophan
Trр, W
Isoleucine
Ile, I
CH3
SH
но.
CH3
но
H3N
co
H3N
co
co
co
Cysteine
Cys, C
Threonine
Thr, T
Serine
Methionine
Met, M
Ser, S
H
H2N
`NH
N°
®NH2
CO2
co
co
H3N
co
Proline
Histidine
Arginine
Arg, R
Lysine
Lys, K
Pro, P
His, H
H2N.
`NH2
H3N'
co
H3N
co
H3Ñ
co
H3N
co
Aspartate
Asp, D
Asparagine
Asn, N
Glutamate
Glutamine
Glu, E
Gln, Q
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