● The total carbonate pool in blood plasma (blood lacking red blood cells) is 0.025M and consist of both HCO3 and CO₂ (aq). The pka for the dissociation of H₂CO3 to produce HCO3 and H* at 37°C is 6.1. Because H₂CO3 is readily produced in blood from dissolved CO₂ (aq) + H2O (a reaction catalyzed by the enzyme carbonic and hydrase), CO₂ (aq) can be considered the conjugate acid and HCO3- the conjugate base in the bicarbonate buffering system. i. What is the ratio of HCO3 and CO₂ (aq) in blood plasma at pH of 7.4? ii. What are the individual concentrations of CO₂ (aq) and HCO3 under these same conditions?

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The total carbonate pool in blood plasma (blood lacking red blood cells) is 0.025M and consists
of both HCO3 and CO₂ (aq). The pka for the dissociation of H₂CO3 to produce HCO3 and H* at
37°C is 6.1. Because H₂CO3 is readily produced in blood from dissolved CO₂ (aq) + H2O
(a reaction catalyzed by the enzyme carbonic andhydrase), CO₂ (aq) can be considered the
conjugate acid and HCO3- the conjugate base in the bicarbonate buffering system.
i. What is the ratio of HCO3 and CO₂ (aq) in blood plasma at pH of 7.4?
ii. What are the individual concentrations of CO₂ (aq) and HCO3 under these same
conditions?
Transcribed Image Text:The total carbonate pool in blood plasma (blood lacking red blood cells) is 0.025M and consists of both HCO3 and CO₂ (aq). The pka for the dissociation of H₂CO3 to produce HCO3 and H* at 37°C is 6.1. Because H₂CO3 is readily produced in blood from dissolved CO₂ (aq) + H2O (a reaction catalyzed by the enzyme carbonic andhydrase), CO₂ (aq) can be considered the conjugate acid and HCO3- the conjugate base in the bicarbonate buffering system. i. What is the ratio of HCO3 and CO₂ (aq) in blood plasma at pH of 7.4? ii. What are the individual concentrations of CO₂ (aq) and HCO3 under these same conditions?
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