The SARS-CoV-2 spike protein binds to the ACE2 receptor protein in humans. A sequence found in the region of the protein that binds ACE2 is listed below. (Science, May 2020) Draw this peptide with the correct R-group structures under physiological conditions, TNGVGY three letter amino acid (AA) symbols and peptide bonds. The Human ACE2 receptor protein is an 805 AA membrane protein and a Zinc metalloenzyme that is displayed in the lungs, heart, kidney, and intestines, smooth muscle and neural cells. (JBC, April 2004) It was recognized as the receptor site for SARS in the early 2000's. ACE2 cleaves angiotensin II to produce the vasodilator angiotensin: DRVYIHP Draw this peptide with the correct R-group structures under physiological conditions, three letter amino acid (AA) symbols and peptide bonds. The Zn metal ion is bond by a conserved protein sequence motif found in about half of all known metalloproteases. The highly conserved AA's are underlined: HEMGH renose a reason for why this AA sequence motif is highly conserved among metalloproteases
The SARS-CoV-2 spike protein binds to the ACE2 receptor protein in humans. A sequence found in the region of the protein that binds ACE2 is listed below. (Science, May 2020) Draw this peptide with the correct R-group structures under physiological conditions, TNGVGY three letter amino acid (AA) symbols and peptide bonds. The Human ACE2 receptor protein is an 805 AA membrane protein and a Zinc metalloenzyme that is displayed in the lungs, heart, kidney, and intestines, smooth muscle and neural cells. (JBC, April 2004) It was recognized as the receptor site for SARS in the early 2000's. ACE2 cleaves angiotensin II to produce the vasodilator angiotensin: DRVYIHP Draw this peptide with the correct R-group structures under physiological conditions, three letter amino acid (AA) symbols and peptide bonds. The Zn metal ion is bond by a conserved protein sequence motif found in about half of all known metalloproteases. The highly conserved AA's are underlined: HEMGH renose a reason for why this AA sequence motif is highly conserved among metalloproteases
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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
Transcribed Image Text:The SARS-CoV-2 spike protein binds to the ACE2 receptor protein in humans. A sequence found in the
region of the protein that binds ACE2 is listed below. (Science, May 2020)
Draw this peptide with the correct R-group structures under physiological conditions,
TNGVGY
three letter amino acid (AA) symbols and peptide bonds.
The Human ACE2 receptor protein is an 805 AA membrane protein and a Zinc metalloenzyme that is
displayed in the lungs, heart, kidney, and intestines, smooth muscle and neural cells. (JBC, April 2004)
It was recognized as the receptor site for SARS in the early 2000's. ACE2 cleaves angiotensin II to produce
the vasodilator angiotensin:
DRVYIHP
Draw this peptide with the correct R-group structures under physiological conditions,
three letter amino acid (AA) symbols and peptide bonds.
The Zn metal ion is bond by a conserved protein sequence motif found in about half of all known
metalloproteases. The highly conserved AA's are underlined:
HEMGH
a reason for why this AA sequence motif is highly conserved among metalloproteases
Expert Solution
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Introduction
An enzyme is a catalyst that speeds up a chemical reaction in the cells. Enzymes are proteins that bind to substrates, change them, and then produce a product.
Amino acids, which are made up of carbon, nitrogen, oxygen, and hydrogen, as well as the side chain or R group, are the building blocks of proteins. Since each amino acid's sidechain or R group is distinct, it distinguishes the amino acids.
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