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The pneumoniae isolates are capable of capsule synthesis. All of the following apply to transformation of Streptococcus pneumoniae EXCEPT

The pneumoniae isolates are capable of capsule synthesis. All of the following apply to transformation of Streptococcus pneumoniae EXCEPT

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The pneumoniae isolates are capable of capsule synthesis. All of the following apply to transformation of Streptococcus pneumoniae EXCEPT Alignment of donor genes with recipient chromosome At risk populations for S. pneumoniae are those <5 and >65 years of age S strains that are 100,000X more virulent than R strains No contact between donor and recipient cells Replacement of recipient genes with donor genes Acquisition of a Vir plasmid carrying capsule- producing genes
Transcribed Image Text:The pneumoniae isolates are capable of capsule synthesis. All of the following apply to transformation of Streptococcus pneumoniae EXCEPT Alignment of donor genes with recipient chromosome At risk populations for S. pneumoniae are those <5 and >65 years of age S strains that are 100,000X more virulent than R strains No contact between donor and recipient cells Replacement of recipient genes with donor genes Acquisition of a Vir plasmid carrying capsule- producing genes
Use the following to answer 4 consecutive questions Case History: A patient is admitted to the Emergency Department with a 3 day history of severe coughing and fever, then is transferred to the ICU with severe bacterial pneumonia (lung infection) caused by Streptococcus pneumoniae. The patient is placed on the fluoroquinolone antibiotic Levaquin (R) and initially improves, however the patient relapses and dies on day 5 of hospitalization. Two cultures were performed at day 1 and 5. The isolates are identical with the exception that the S. pneumoniae cultured from day 1 has a point mutation in the parC gene and is susceptible to Levaquin while the S. pneumoniae cultured from day 5 has point mutations in both the parC and gyrA genes and is resistant to Levaquin. The patient dies on day 5 from pneumonia and sepsis
Transcribed Image Text:Use the following to answer 4 consecutive questions Case History: A patient is admitted to the Emergency Department with a 3 day history of severe coughing and fever, then is transferred to the ICU with severe bacterial pneumonia (lung infection) caused by Streptococcus pneumoniae. The patient is placed on the fluoroquinolone antibiotic Levaquin (R) and initially improves, however the patient relapses and dies on day 5 of hospitalization. Two cultures were performed at day 1 and 5. The isolates are identical with the exception that the S. pneumoniae cultured from day 1 has a point mutation in the parC gene and is susceptible to Levaquin while the S. pneumoniae cultured from day 5 has point mutations in both the parC and gyrA genes and is resistant to Levaquin. The patient dies on day 5 from pneumonia and sepsis
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