The oxidation of the branch chain amino acids (leucine, isoleucine and valine) by the mitochondrion yields large amounts of succinate and acetyl CoA. In isolated cells, what effect would high leucine, isoleucine and valine oxidation have on energy charge, glycolysis and gluconeogenesis in the liver?
Organic Chemistry of Metabolic Pathways
Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.
Glucogenesis
Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general definition for glucogenesis or gluconeogenesis is as follows,
The oxidation of the branch chain amino acids (leucine, isoleucine and valine) by the mitochondrion yields large amounts of succinate and acetyl CoA. In isolated cells, what effect would high leucine, isoleucine and valine oxidation have on energy charge, glycolysis and gluconeogenesis in the liver?
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