The nuclear export cycle is shown in the diagram. nuclear export receptor [Select] cargo. [Select] cytosol. [Select] You have discovered a drug that blocks the ability of Ran to hydrolyze GTP. Predict what is likely to happen when a cell is treated with this drug for a prolonged period of time by indicating true or false for each of the following scenarios. Nuclear export receptors in the nucleus would still be able to bind [Select] 1 S DC Ran-GTP cargo delivered to cytosol Ran-GTP BINDS TO RECEPTORS Ran-GDP protein with nuclear export signal (cargo) ✓ Nuclear export receptors would still be able to release cargo in the Eventually, all Ran proteins will be in the GTP binding form. ✓ Nuclear export will continue normally.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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for question 1, choose wheater each statement is true or false

for quesiton 2, choose the wheater each statement is true or false

The nuclear export cycle is shown in the diagram.
nuclear export
receptor
cargo.
[Select]
cytosol.
[Select]
You have discovered a drug that blocks the ability of Ran to hydrolyze GTP. Predict what is likely to
happen when a cell is treated with this drug for a prolonged period of time by indicating true or
false for each of the following scenarios.
[Select]
Nuclear export receptors in the nucleus would still be able to bind
[Select]
cargo delivered to cytosol
Ran-GTP
Ran-GTP BINDS TO
RECEPTORS
Ran-GDP
DC
protein with nuclear
export signal (cargo)
✓ Nuclear export receptors would still be able to release cargo in the
✓ Eventually, all Ran proteins will be in the GTP binding form.
✓ Nuclear export will continue normally.
Transcribed Image Text:The nuclear export cycle is shown in the diagram. nuclear export receptor cargo. [Select] cytosol. [Select] You have discovered a drug that blocks the ability of Ran to hydrolyze GTP. Predict what is likely to happen when a cell is treated with this drug for a prolonged period of time by indicating true or false for each of the following scenarios. [Select] Nuclear export receptors in the nucleus would still be able to bind [Select] cargo delivered to cytosol Ran-GTP Ran-GTP BINDS TO RECEPTORS Ran-GDP DC protein with nuclear export signal (cargo) ✓ Nuclear export receptors would still be able to release cargo in the ✓ Eventually, all Ran proteins will be in the GTP binding form. ✓ Nuclear export will continue normally.
For each of the following statements regarding protein import into mitochondria, indicate whether it
is likely to be true or false.
[Select]
into the mitochondria matrix.
[Select]
[Select]
being translated
[Select]
unfolded state.
The signal sequence is always retained after proteins are imported
Chaperon proteins are needed for protein import into mitochondria
Imported proteins cross the mitochondrial membrane while it is still
✓ Proteins imported into mitochondria cross the membrane in
Transcribed Image Text:For each of the following statements regarding protein import into mitochondria, indicate whether it is likely to be true or false. [Select] into the mitochondria matrix. [Select] [Select] being translated [Select] unfolded state. The signal sequence is always retained after proteins are imported Chaperon proteins are needed for protein import into mitochondria Imported proteins cross the mitochondrial membrane while it is still ✓ Proteins imported into mitochondria cross the membrane in
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