The NIH is funding a trial for a new antidepressant drug. A sample of 1000 people with severe depression are recruited and, at baseline, are given a questionnaire asking about their demographic characteristics and their mental health. They are then randomly assigned to one of two groups. The treatment group receives the new antidepressant, a pill that must be taken twice a day. The control group receives a placebo pill containing nothing medically active, which must also be taken twice a day. After 10 weeks, researche
The NIH is funding a trial for a new antidepressant drug. A sample of 1000 people with severe depression are recruited and, at baseline, are given a questionnaire asking about their demographic characteristics and their mental health. They are then randomly assigned to one of two groups. The treatment group receives the new antidepressant, a pill that must be taken twice a day. The control group receives a placebo pill containing nothing medically active, which must also be taken twice a day. After 10 weeks,
researchers locate the individuals and ask them to fill out a questionnaire again assessing their mental health. At the end of the study, researchers find no statistically significant difference in the mental health of the treatment and control groups.
Question: If these 1000 people lived in 1000 different cities, would spillovers be a concern? If these 1000 people all lived in Arlington, VA, would spillovers be a concern? Explain as specifically as you can how spillovers might cause such underestimation of the true impact of the drug.
![](/static/compass_v2/shared-icons/check-mark.png)
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
![MATLAB: An Introduction with Applications](https://www.bartleby.com/isbn_cover_images/9781119256830/9781119256830_smallCoverImage.gif)
![Probability and Statistics for Engineering and th…](https://www.bartleby.com/isbn_cover_images/9781305251809/9781305251809_smallCoverImage.gif)
![Statistics for The Behavioral Sciences (MindTap C…](https://www.bartleby.com/isbn_cover_images/9781305504912/9781305504912_smallCoverImage.gif)
![MATLAB: An Introduction with Applications](https://www.bartleby.com/isbn_cover_images/9781119256830/9781119256830_smallCoverImage.gif)
![Probability and Statistics for Engineering and th…](https://www.bartleby.com/isbn_cover_images/9781305251809/9781305251809_smallCoverImage.gif)
![Statistics for The Behavioral Sciences (MindTap C…](https://www.bartleby.com/isbn_cover_images/9781305504912/9781305504912_smallCoverImage.gif)
![Elementary Statistics: Picturing the World (7th E…](https://www.bartleby.com/isbn_cover_images/9780134683416/9780134683416_smallCoverImage.gif)
![The Basic Practice of Statistics](https://www.bartleby.com/isbn_cover_images/9781319042578/9781319042578_smallCoverImage.gif)
![Introduction to the Practice of Statistics](https://www.bartleby.com/isbn_cover_images/9781319013387/9781319013387_smallCoverImage.gif)