The next transformation that our lab performs on the product obtained in this lab is reduction to obtain the mono-bromo cyclopropane (B to C). One possible isomer is shown below. What are the expected coupling constants for the proton highlighted in orange? (Hint: recall the Karplus curve)

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter31: Immunochemistry
Section: Chapter Questions
Problem 31.75P
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The next transformation that our lab performs on the product obtained in this lab is reduction to obtain the mono-bromo cyclopropane (B to C). One possible isomer is shown below. What are the expected coupling constants for the proton highlighted in orange? (Hint: recall the Karplus curve)

Br.
H
H
CH3
H
Transcribed Image Text:Br. H H CH3 H
CHBR3
NaOH
P(OH)(OEt)2
Br
BTEAC
t-BUOK
丈
t-BUOK
Br
-Br
DMSO
DCM,
reflux
Ph
Me
Ph
Me
DMSO
A
В
Transcribed Image Text:CHBR3 NaOH P(OH)(OEt)2 Br BTEAC t-BUOK 丈 t-BUOK Br -Br DMSO DCM, reflux Ph Me Ph Me DMSO A В
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