The next four questions refer to a case study of an influenza infection in an example individual.  The details of the case study are presented here; please refer to them when answering the next four questions. -------------------------- Index (First) Case: A miner aged 38 years who worked at copper mine X. On August 11, the miner had onset of coughing and a sore throat, but continued coming to work.  On August 16, with worsening signs and symptoms including fatigue, muscle aches, vomiting, and uncontrollable coughing, the patient was admitted to a hospital, where a chest radiograph showed bilateral infiltrates.  Sputum cultures were negative but showed increased leukocyte counts.  The patient was transferred to intensive care on August 21 and was treated with intravenous antibiotics (trimethoprim), which did not resolve symptoms.  Patient samples tested positive for H1N1 influenza virus in PCR and ELISA assays, and the patient was treated with oseltamivir to inhibit viral spread.  Viral titers were observed to decrease beginning on August 24, concomitant with a lessening of symptoms, and the patient was released on August 29 with no detectable virus. Fifteen of the patient’s co-workers and thirty individuals exposed at the hospital came down with respiratory symptoms and tested positive for H1N1 influenza in the following two weeks.  All were treated with oseltamivir and recovered.   Refer to the case study above. For the index case described, why was trimethoprim not useful? Group of answer choices Influenza has acquired resistance to this antibiotic over time The patient was resistant to trimethoprim A viral infection would not respond to an antibiotic The patient did not take the antibiotic for a long enough time   Refer to the case study above.  When was the index case patient least likely to spread the infection to others? Group of answer choices August 16 – August 23 August 11 – August 29 August 11 – August 15 After August 29   Refer to the case study above.  For the index case described, what was the incubation period? Group of answer choices August 16 – August 19 August 11 – August 15 August 21 – August 23 The answer cannot be determined from the data provided   Refer to the case study above. Which of the following were signs (not symptoms) associated with the infection?  Choose all that apply. Group of answer choices Muscle aches Vomiting Leukocytes in sputum sample Fatigue

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The next four questions refer to a case study of an influenza infection in an example individual.  The details of the case study are presented here; please refer to them when answering the next four questions.

--------------------------

Index (First) Case: A miner aged 38 years who worked at copper mine X.

On August 11, the miner had onset of coughing and a sore throat, but continued coming to work.  On August 16, with worsening signs and symptoms including fatigue, muscle aches, vomiting, and uncontrollable coughing, the patient was admitted to a hospital, where a chest radiograph showed bilateral infiltrates.  Sputum cultures were negative but showed increased leukocyte counts.  The patient was transferred to intensive care on August 21 and was treated with intravenous antibiotics (trimethoprim), which did not resolve symptoms.  Patient samples tested positive for H1N1 influenza virus in PCR and ELISA assays, and the patient was treated with oseltamivir to inhibit viral spread.  Viral titers were observed to decrease beginning on August 24, concomitant with a lessening of symptoms, and the patient was released on August 29 with no detectable virus.

Fifteen of the patient’s co-workers and thirty individuals exposed at the hospital came down with respiratory symptoms and tested positive for H1N1 influenza in the following two weeks.  All were treated with oseltamivir and recovered.

 

Refer to the case study above. For the index case described, why was trimethoprim not useful?
Group of answer choices
Influenza has acquired resistance to this antibiotic over time
The patient was resistant to trimethoprim
A viral infection would not respond to an antibiotic
The patient did not take the antibiotic for a long enough time
 
Refer to the case study above.  When was the index case patient least likely to spread the infection to others?
Group of answer choices
August 16 – August 23
August 11 – August 29
August 11 – August 15
After August 29
 
Refer to the case study above.  For the index case described, what was the incubation period?
Group of answer choices
August 16 – August 19
August 11 – August 15
August 21 – August 23
The answer cannot be determined from the data provided
 
Refer to the case study above. Which of the following were signs (not symptoms) associated with the infection?  Choose all that apply.
Group of answer choices
Muscle aches
Vomiting
Leukocytes in sputum sample
Fatigue
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