The molecular weight of hemoglobin is 64,500 daltons (= g mol-1). A. How much oxygen can be bound per g of hemoglobin? Express the values as mL per g of hemoglobin, where mL is the volume of O2. R =0.082 L atm mol-1 oK-1, oK =273 + oC. The molar volume of O2 is given as V = nRT/P where P = 1 atm and n= 1 mol. (Hint: 1.0 mol x 0.082 L atm mol-1 oK-1 x 273.2 oK / 1 atm = 22.4 L mol-1) (Hint: The number of moles of O2 that can be bound per g of hemoglobin is 4 x the moles of Hb in 1 g). B. The blood in a person contains 15 g of hemoglobin per 100 ml blood. How much oxygen does the blood contain at 95 mm Hg if hemoglobin is 98% saturated and the solubility of O2 is 0.003 mL dL-1 mmHg-1? (Hint: Total O2 content = HbO2 + free dissolved O2) C. Suppose the venous PO2 is 40 mm Hg, and that hemoglobin is 75% saturated at this point. What is the oxygen content of venous blood?
Ideal and Real Gases
Ideal gases obey conditions of the general gas laws under all states of pressure and temperature. Ideal gases are also named perfect gases. The attributes of ideal gases are as follows,
Gas Laws
Gas laws describe the ways in which volume, temperature, pressure, and other conditions correlate when matter is in a gaseous state. The very first observations about the physical properties of gases was made by Robert Boyle in 1662. Later discoveries were made by Charles, Gay-Lussac, Avogadro, and others. Eventually, these observations were combined to produce the ideal gas law.
Gaseous State
It is well known that matter exists in different forms in our surroundings. There are five known states of matter, such as solids, gases, liquids, plasma and Bose-Einstein condensate. The last two are known newly in the recent days. Thus, the detailed forms of matter studied are solids, gases and liquids. The best example of a substance that is present in different states is water. It is solid ice, gaseous vapor or steam and liquid water depending on the temperature and pressure conditions. This is due to the difference in the intermolecular forces and distances. The occurrence of three different phases is due to the difference in the two major forces, the force which tends to tightly hold molecules i.e., forces of attraction and the disruptive forces obtained from the thermal energy of molecules.
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