**Michaelis–Menten Equation: Understanding Substrate Concentration and Reaction Rate**The Michaelis–Menten equation describes the relationship between the initial velocity \( V_0 \) of an enzymatic reaction and the substrate concentration \([S]\). Understanding this relationship helps in determining how changes in \([S]\) affect the reaction rate.**Match the Conditions with the Corresponding Statements:**1. **Doubling \([S]\) will almost double the rate.**2. **Half of the active sites are occupied by substrate.**3. **About 90% of the active sites are occupied by substrate.**4. **Doubling \([S]\) will have little effect on the rate.**5. **Less than 10% of the active sites are occupied by substrate.**6. **This condition will result in the highest rate.****Answer Bank:**- \([S] = 0.1 \, K_m\)- \([S] = K_m\)- \([S] = 10 \, K_m\)**Explanation:**- **\([S] = 0.1 \, K_m\):** - Doubling \([S]\) will almost double the rate. - Less than 10% of the active sites are occupied by substrate.- **\([S] = K_m\):** - Half of the active sites are occupied by substrate.- **\([S] = 10 \, K_m\):** - About 90% of the active sites are occupied by substrate. - Doubling \([S]\) will have little effect on the rate. - This condition will result in the highest rate.

The Michaelis-Menten equation is an expression of the relationship between the initial velocity Vo of an enzymatic reaction and substrate concentration [S]. There are three conditions that are useful for simplifying the Michaelis–Menten equation to an expression from which the effect of [S] on the rate can be more readily determined. Match the condition (e.g., [S] = Km) with the statement or statements that describe it. Doubling [S] will almost double the rate. Half of the active sites are occupied by substrate. About 90% of the active sites are occupied by substrate. Doubling [S] will have little effect on the rate. Less than 10% of the active sites are occupied by substrate. This condition will result in the highest rate. Answer Bank [S] = 0.1 Km [S] = Km [S] = 10 Km

The Michaelis-Menten equation is an expression of the relationship between the initial velocity Vo of an enzymatic reaction and substrate concentration [S]. There are three conditions that are useful for simplifying the Michaelis–Menten equation to an expression from which the effect of [S] on the rate can be more readily determined. Match the condition (e.g., [S] = Km) with the statement or statements that describe it. Doubling [S] will almost double the rate. Half of the active sites are occupied by substrate. About 90% of the active sites are occupied by substrate. Doubling [S] will have little effect on the rate. Less than 10% of the active sites are occupied by substrate. This condition will result in the highest rate. Answer Bank [S] = 0.1 Km [S] = Km [S] = 10 Km

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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