The macrocyclic ester L can be prepared by a ring closing metathesis (RCM)-alkene reduction strategy as outlined below. Answer sections (i) to (iii) related to this process. L M N OH CO₂H (i) Draw the structure of a ruthenium-based catalyst commonly used for RCM and provide a simplified reaction mechanism for the RCM of diene M. (ii) Disconnect M and show the resultant synthons which correspond to alcohol N and carboxylic acid O. (iii) Based on your answer to section (ii), discuss the forward reaction to form M mentioning any additional reagents and explaining their role.

The macrocyclic ester L can be prepared by a ring closing metathesis (RCM)-alkene reduction strategy as outlined below. Answer sections (i) to (iii) related to this process. L M N OH CO₂H (i) Draw the structure of a ruthenium-based catalyst commonly used for RCM and provide a simplified reaction mechanism for the RCM of diene M. (ii) Disconnect M and show the resultant synthons which correspond to alcohol N and carboxylic acid O. (iii) Based on your answer to section (ii), discuss the forward reaction to form M mentioning any additional reagents and explaining their role.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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