The Friedel-Crafts acylation reaction of compound Q and 2-(1-phenylethyl)-1,3-dioxolane was also found to give a second unknown compound, which 1 H NMR spectroscopy suggested was a regioisomer of intermediate R. Suggest a structure for this second unknown compound. The synthesis of suprofen, a potent non-steroidal anti-inflammatory drug, from thiophene is proposedfollowing the sequence of reactions shown below.H3CH.CHз (DMF)POCI3stepsNa,CO3, H20HCIthiopheneAICI3CH32-(1-phenylethyl)-1,3-dioxolanestepsHO2CS.CH3CH3Rsuprofen

regioisomers are the isomers that have same molecular formula but differ with respect to position of…

Answered: The Friedel-Crafts acylation reaction…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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The Friedel-Crafts acylation reaction of compound Q and 2-(1-phenylethyl)-1,3-dioxolane was also found to give a second unknown compound, which 1 H NMR spectroscopy suggested was a regioisomer of intermediate R. Suggest a structure for this second unknown compound.

The synthesis of suprofen, a potent non-steroidal anti-inflammatory drug, from thiophene is proposed
following the sequence of reactions shown below.
H3C
H.
CHз (DMF)
POCI3
steps
Na,CO3, H20
H
CI
thiophene
AICI3
CH3
2-(1-phenylethyl)-
1,3-dioxolane
steps
HO2C
S.
CH3
CH3
R
suprofen

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