The formation of an acetal from a ketone or aldehyde has a very similar mechanism to the formation of an imine (review Equations 18-13 and 18-19). Both require acidic conditions to generate a water leaving group. At very acidic pH, however, the rate of imine formation slows down (see the accompanying graph), whereas the rate of acetal formation does not. Explain this pH dependence of imine formation. 1 2 3 4 6 7 pH Rate of imine formation –>

The formation of an acetal from a ketone or aldehyde has a very similar mechanism to the formation of an imine (review Equations 18-13 and 18-19). Both require acidic conditions to generate a water leaving group. At very acidic pH, however, the rate of imine formation slows down (see the accompanying graph), whereas the rate of acetal formation does not. Explain this pH dependence of imine formation. 1 2 3 4 6 7 pH Rate of imine formation –>

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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