The following molecule is formed in a mixed aldol condensation reaction. organic starting materials B-hydroxycarbonyl но NaOH

Q: Explain why ketone K undergoes aldol reactions but ketone J does not.

A: Given molecules:

Q: What compound cannot undergo an aldolreaction? H I- IV CHO CHO

A: Approach to solving the question: Detailed explanation: Examples: Key references:

Q: 4 H20 HODN H

A: In the cross aldol reaction, four different products are possible from the two different aldehydes…

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

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Q: Use the malonic ester synthesis to prepare each carboxylic acid.

A: Melonic ester synthesis method is used to synthesise carboxylic acids with desired carbon chain.

Q: draw the product formed if this compound will undergo acid-catalyzed fischer esterification

A: When 3-isopropyl pentan-5-ol-1-oic acid undergoes acid catalyzed Fischer esterification in presence…

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: Please see attachment below for product and mechanism Explanation:Step 1: Step 2:Mechanism   Step 3:…

Q: What sequence of reactions would allow a conversion of an ester to an anhydride? NaOH SOCI, NaOH…

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Q: Draw a stepwise mechanism for the following variation of the aldol reaction, often called a nitro…

A: Since the OH- will extract a proton from the alpha position in the molecule. And since only CH3NO2…

Q: Choose the correct product for the following reaction 4-methylcyclohexanone + Br2/H3O+ --> product?…

A: Answer:In this problem, given substrate is a ketone and we have to find out the product forming when…

Q: 11. two moles of ethyl phenylacetate undergo condensation to give a beta-keto ester. 12. a…

A: We have to write the structures of the following reactions 11. two moles of ethyl phenylacetate…

Q: i Ph Ph NaOH, acetone, Ph Ph

A: The given reaction is an example of Robinson annulation reaction. The reaction is a Michael addition…

Q: Orsellinic acid, a common constituent of lichens, is synthesized from the condensation of acetyl…

A: Concept introduction: The orsellinic acid is most commonly found in lichens. It can be synthesized…

Q: addition of hydrogen cyanide to an aldehyde

A: Thank you.

Q: Why is the Aldol reaction often called an Aldol condensation? O 1) The initially formed b-hydroxy…

A: The question is based on the concept of organic reactions. We have to identify the reason for…

Q: Draw a stepwise mechanism for the following variation of the aldol reaction, often called a nitro…

A: The given reaction is,

Q: Procyclidine is a drug that has been used to treat the uncontrolled body movements associated with…

A: INTRODUCTION: The formation of grignard reagent is shown below: EXPLANATION: When ketone reacts…

Q: 4) The following enone, 3-methylcyclopent-2-enone, was prepared through an intramolecular aldol…

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Q: H روه Base Aldol Product the Mal NaOH H₂0 Condensation Product

A: Organic reactions are those in which organic reactant react to form organic products. In the given…

Q: Draw the structures A, B and C for the reaction sequence below. Michael Reaction A Dehydration via…

A: Given are 3 reactions. Michael reaction,  aldol condensation and dehydration.

Q: The following molecular model represents the tetrahedral intermediate resulting from addition of a…

A: It is an alcohol and an aldehyde reaction.

Q: 2-Pentylcinnamaldehyde, commonly called flosal, is a perfume ingredient with a jasminelike odor.…

A: The aldehydes containing alpha-H reacts with base (diluted) and furnishes beta-hydroxy aldehydes…

Q: CH3 + MeOH H.

A: I have drawn all the structures via neutral mechanism, hemiacetal structure is independent of the…

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

A: Aldol Reactions:- Those reactions in which two aldehydes or two ketones or one aldehyde and one…

Q: Draw the step-by-step mechanism of the following hydrolysis of nitrile compound in acidic and basic…

A: In Hydrolysis, lysis means breaking of bond between carbon and oxygen in water molecule. In cyanide…

Q: Draw the keto- tautomer for the following enols

A: Tautomers have two form keto form and enol form both keto and enol form are in equilibrium with each…

Q: Please come up with five ways to synthesize α,β-Unsaturated carbonyl compounds. Draw reaction…

A: The question is based on the concept of organic reactions. We have to identify the reactions which…

Q: What is the general name for

A: With alpha-H containing carbonyl compounds in presence of dilute base ( like dil NaOH, dil KOH,…

Q: ArSO,H Draw curved arrows to show the movement of electrons in the following step of an…

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Q: base H&C OH heat + H₂O The aldol reaction is a carbonyl condensation reaction between two carbonyl…

A: The objective of the question is to draw the curved arrow to show the electron movement for the…

Q: base 2 H3C H H3C OH heat H H3C + H₂O H The aldol reaction is a carbonyl condensation reaction…

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Q: This reaction is an example of conjugate addition of a nucleophile to an a.B-unsaturated carbonyl.…

A: conjugate 1,4 addition is called Michael addition

Q: In the reaction shown below draw curly arrows to show how the acetylide can act as a nucleophile.

A: The following steps are involved in the attack of acetylide as a nucleophile over acetone: The…

Q: Ph OMe Ph HO

A: Given transformation is,

Q: What are the products of an aldol cyclization for the following compound?

A: We have to predict the cyclization products.

Q: 5. Consider the below aldol reaction. Draw the product if all reactants are consumed and…

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Q: Draw the products that result from each step in the synthesis of m-bromoaniline. HNO3, H2SO4 Step 1…

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.