The first-order degradation of a drug was monitored under three different conditions (I, ii, and iii), which resulted in half-lives (in no particular order) of 4 hours, 8 hours, and 10 hours: i. at 37 °C. ii. at 37 °C, in the presence of a catalyst. iii. at 21 C. Identify which half life goes with which set of conditions. For condition i., draw and label a graph of Concentration (mmol/L) vs Time (hr). Start with an initial concentration of 10 mmol/L and show the decay over 40 hours. You may use the grid below or draw your graph by hand.
The first-order degradation of a drug was monitored under three different conditions (I, ii, and iii), which resulted in half-lives (in no particular order) of 4 hours, 8 hours, and 10 hours: i. at 37 °C. ii. at 37 °C, in the presence of a catalyst. iii. at 21 C. Identify which half life goes with which set of conditions. For condition i., draw and label a graph of Concentration (mmol/L) vs Time (hr). Start with an initial concentration of 10 mmol/L and show the decay over 40 hours. You may use the grid below or draw your graph by hand.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:The first-order degradation of a drug was monitored under three different conditions (I, ii, and
iii), which resulted in half-lives (in no particular order) of 4 hours, 8 hours, and 10 hours:
а.
i. at 37 °C.
ii. at 37 °C, in the presence of a catalyst.
iii. at 21 °C.
Identify which half life goes with which set of conditions.
For condition i., draw and label a graph of Concentration (mmol/L) vs Time (hr). Start with an
initial concentration of 10 mmol/L and show the decay over 40 hours. You may use the grid
below or draw your graph by hand.
10
9.5
8.5
7.5
2 6.5
E 5.5
4.5
4
3.5
2.5
1.5
0.5
4
8
10
12
14
16
18 20 22
24 26
28
30
32
34
36
38
40
Time (hours)
-1
Another reaction is found to have an activation energy of 80.3 kJmol. The reaction is
very slow at 25°c. Which will be the more effective way of speeding up the reaction,
b.
-1
i. adding a catalyst which lowers the activation energy to 30.0 kJ mol or
ii. raising the temperature from 25°C to 50°C ?
Show all calculations and explain your final conclusion.
Concentration (mmol/L)
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