The Claisen condensation converts two molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. in 1. "OCH,CH3 / CH;CH2OH 2 2. H30* Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an enolate resonance form is possible, draw only the carbanionic form. If a CH, group is being deprotonated, draw all H's on the reacting site. Tip: always omit ethanol byproducts. tep 4c: Draw the resulting structure or structures indicated by the curved-arrow mechanism shown. Include formal charges, ut not lone pairs. :0: :0: H H 1

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Step 4c: Draw the resulting structure or structures indicated by the curved‑arrow mechanism shown. Include formal charges, but not lone pairs.

The Claisen condensation converts two molecules of an ester into a B-keto ester. The reaction starts with the ester in an
alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product.
1. ОСH-CH3/ CHCH2OH
2. H30*
он
Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all
formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an enolate
resonance form is possible, draw only the carbanionic form. If a CHx group is being deprotonated, draw all H's on the
reacting site. Tip: always omit ethanol byproducts.
Step 4c: Draw the resulting structure or structures indicated by the curved-arrow mechanism shown. Include formal charges,
but not lone pairs.
:0:
:0:
H H
H
Transcribed Image Text:The Claisen condensation converts two molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. 1. ОСH-CH3/ CHCH2OH 2. H30* он Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an enolate resonance form is possible, draw only the carbanionic form. If a CHx group is being deprotonated, draw all H's on the reacting site. Tip: always omit ethanol byproducts. Step 4c: Draw the resulting structure or structures indicated by the curved-arrow mechanism shown. Include formal charges, but not lone pairs. :0: :0: H H H
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