**Text Transcription:**5. Suggest a forward synthesis for the following retrosynthetic analysis of the target molecule. Begin with the labeled starting material and be sure to include the synthetic equivalent (SE-1) in your synthesis.**Diagram Explanation:**- **Target Molecule:** A six-membered aromatic ring with two carbonyl groups (C=O) attached directly to the ring.- **Synthetic Equivalent (SE-1):** A derivative of the target molecule with two ester groups (CO₂Et and EtO₂C) attached to the ring, showing a more complex intermediate structure.- **Starting Material:** A linear molecule with two ester groups on either end (EtO₂C and another with CO₂Et) connected by a two-carbon chain.The diagram illustrates a synthetic pathway using retrosynthetic analysis, progressing from the target molecule to a more complex SE-1 intermediate, and finally to the simpler starting material.

Target and starting material are given. We have to make target molecule from starting material. The reaction proceeds via formation of enolate ion which then acts as a nucleophile. Two consecutive enolate reactions followed by basic hydrolysis and then decarboxylation reaction.

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target molecule. Begin with the labeled starting material and be sure to include the synthetic equivalent (SE-1) in your synthesis. Target Molecule EtO₂C SE-1 CO₂Et EtO₂C CO₂Et Starting Material

target molecule. Begin with the labeled starting material and be sure to include the synthetic equivalent (SE-1) in your synthesis. Target Molecule EtO₂C SE-1 CO₂Et EtO₂C CO₂Et Starting Material

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

**Text Transcription:**

5. Suggest a forward synthesis for the following retrosynthetic analysis of the target molecule. Begin with the labeled starting material and be sure to include the synthetic equivalent (SE-1) in your synthesis.

**Diagram Explanation:**

- **Target Molecule:** A six-membered aromatic ring with two carbonyl groups (C=O) attached directly to the ring.

- **Synthetic Equivalent (SE-1):** A derivative of the target molecule with two ester groups (CO₂Et and EtO₂C) attached to the ring, showing a more complex intermediate structure.

- **Starting Material:** A linear molecule with two ester groups on either end (EtO₂C and another with CO₂Et) connected by a two-carbon chain.

The diagram illustrates a synthetic pathway using retrosynthetic analysis, progressing from the target molecule to a more complex SE-1 intermediate, and finally to the simpler starting material.

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