TABLE 5.1 Properties of the common amino acids found in proteins pka of a-COOH Group pKa of a-NH Group pKa of lonizing Side Chain Residue Mass (daltons) Occurrence in Proteins (mol %) Abbreviations: 1- Name and 3-letter codes Alanine А, Ala 2.3 9.7 71.08 8.7 Arginine R, Arg 2.2 9.0 12.5 156.20 5.0 Asparagine N, Asn 2.0 8.8 114.11 4.2 Aspartic acid D, Asp 2.1 9.8 3.9 115.09 5.9 C, Cys Q, Gln E, Glu Cysteine 1.8 10.8 8.3 103.14 1.3 Glutamine 2.2 9.1 128.14 3.7 Glutamic acid 2.2 9.7 4.2 129.12 6.6 Glycine G, Gly 2.3 9.6 57.06 7.9 Н, His I, lle Histidine 1.8 9.2 6.0 137.15 2.4 Isoleucine 2.4 9.7 113.17 5.5 Leucine L, Leu 2.4 9.6 113.17 8.9 K, Lys М, Met Lysine 2.2 9.0 10.0 128.18 5.5 Methionine 2.3 9.2 131.21 2.0 Phenylalanine F, Phe 1.8 9.1 147.18 4.0 Proline P, Pro 2.0 10.6 97.12 4.7 Serine S, Ser 2.2 9.2 87.08 5.8 Threonine T, Thr 2.6 10.4 101.11 5.6 Tryptophan W, Trp 2.4 9.4 186.21 1.5 Tyrosine Y, Tyr 2.2 9.1 10.1 163.18 3.5 Valine V, Val 2.3 9.6 99.14 7.2
TABLE 5.1 Properties of the common amino acids found in proteins pka of a-COOH Group pKa of a-NH Group pKa of lonizing Side Chain Residue Mass (daltons) Occurrence in Proteins (mol %) Abbreviations: 1- Name and 3-letter codes Alanine А, Ala 2.3 9.7 71.08 8.7 Arginine R, Arg 2.2 9.0 12.5 156.20 5.0 Asparagine N, Asn 2.0 8.8 114.11 4.2 Aspartic acid D, Asp 2.1 9.8 3.9 115.09 5.9 C, Cys Q, Gln E, Glu Cysteine 1.8 10.8 8.3 103.14 1.3 Glutamine 2.2 9.1 128.14 3.7 Glutamic acid 2.2 9.7 4.2 129.12 6.6 Glycine G, Gly 2.3 9.6 57.06 7.9 Н, His I, lle Histidine 1.8 9.2 6.0 137.15 2.4 Isoleucine 2.4 9.7 113.17 5.5 Leucine L, Leu 2.4 9.6 113.17 8.9 K, Lys М, Met Lysine 2.2 9.0 10.0 128.18 5.5 Methionine 2.3 9.2 131.21 2.0 Phenylalanine F, Phe 1.8 9.1 147.18 4.0 Proline P, Pro 2.0 10.6 97.12 4.7 Serine S, Ser 2.2 9.2 87.08 5.8 Threonine T, Thr 2.6 10.4 101.11 5.6 Tryptophan W, Trp 2.4 9.4 186.21 1.5 Tyrosine Y, Tyr 2.2 9.1 10.1 163.18 3.5 Valine V, Val 2.3 9.6 99.14 7.2
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
Related questions
Question
Given the following peptide
SEPIMAPVEYPK
(a) Estimate the net charge at pH 7 and at pH 12. Assume the pKa values
given in Table (b) How many peptides would result if this peptide were treated with
(1) cyanogen bromide, (2) trypsin, or (3) chymotrypsin?
(c) Suggest a method for separating the peptides produced by chymotrypsin
treatment.
Transcribed Image Text:TABLE 5.1 Properties of the common amino acids found in proteins
pka of a-COOH
Group
pKa of a-NH
Group
pKa of lonizing
Side Chain
Residue Mass
(daltons)
Occurrence in
Proteins (mol %)
Abbreviations: 1-
Name
and 3-letter codes
Alanine
А, Ala
2.3
9.7
71.08
8.7
Arginine
R, Arg
2.2
9.0
12.5
156.20
5.0
Asparagine
N, Asn
2.0
8.8
114.11
4.2
Aspartic acid
D, Asp
2.1
9.8
3.9
115.09
5.9
C, Cys
Q, Gln
E, Glu
Cysteine
1.8
10.8
8.3
103.14
1.3
Glutamine
2.2
9.1
128.14
3.7
Glutamic acid
2.2
9.7
4.2
129.12
6.6
Glycine
G, Gly
2.3
9.6
57.06
7.9
Н, His
I, lle
Histidine
1.8
9.2
6.0
137.15
2.4
Isoleucine
2.4
9.7
113.17
5.5
Leucine
L, Leu
2.4
9.6
113.17
8.9
K, Lys
М, Met
Lysine
2.2
9.0
10.0
128.18
5.5
Methionine
2.3
9.2
131.21
2.0
Phenylalanine
F, Phe
1.8
9.1
147.18
4.0
Proline
P, Pro
2.0
10.6
97.12
4.7
Serine
S, Ser
2.2
9.2
87.08
5.8
Threonine
T, Thr
2.6
10.4
101.11
5.6
Tryptophan
W, Trp
2.4
9.4
186.21
1.5
Tyrosine
Y, Tyr
2.2
9.1
10.1
163.18
3.5
Valine
V, Val
2.3
9.6
99.14
7.2
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 4 steps with 4 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY