Table 1. Prevalence of HIV-1 in Needles Tested before and during the Syringe-Exchange Program. No. No. HIV- PERCENT HIV-POSITIVE (95% CI) CATEGORY OF NEEDLE TESTED POSITIVE Used before needle exchange, Nov.-Dec. 1990 160 108 68 (60-75) Exchanged illegally 180 113 63 (56-70) Exchanged through the program Nov.-Dec. 1990 Jan. 1991 274 160 175 91 Feb.-April 1991 May-July 1991 Aug.-Oct. 1991 64 (58-70) 57 (49-64) 41 (36-46) 41 (35-46) 42 (37-47) 49 (43-54) 347 141 343 139 166 398 338 Nov.-Dec. 1991 164

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1. In a test of a random sample of 160 needles that were employed by injection-drug users before the exchange program was started,108 were found to be HIV-positive.
 
a.) Construct a 95% confidence interval for the true percentage of all such
pre-exchange needles of injection-drug users found to be HIV-positive.
You can use STATCRUNCH, but you must show the proper formula and plug the correct values into this formula to receive full credit.
FORMULA WITH VALUES: _________________________________
FINAL CONFIDENCE INTERVAL: _________________________________
 
b.) Finish the following sentence. We are 95% confident that ...
 
c) Visit the following site: http://www.nejm.org/doi/full/10.1056/NEJM199212243272613 OR look at the below table attached. Notice Table 1. Find the row Nov. –Dec. 1991. Fill in the values
N =
x =
p =
95% CI =
 
d) Interpret this confidence interval.
 
e)Was the study mentioned an experimental or observational study?
Explain.
 
f) Can one conclude that the exchange program causes a lower rate of HIV?
Why or why not?
What does this give evidence to?
Table 1. Prevalence of HIV-1 in Needles Tested before and
during the Syringe-Exchange Program.
No.
No. HIV-
PERCENT HIV-POSITIVE
(95% CI)
CATEGORY OF NEEDLE
TESTED
POSITIVE
Used before needle exchange,
Nov.-Dec. 1990
160
108
68 (60-75)
Exchanged illegally
180
113
63 (56-70)
Exchanged through the
program
Nov.-Dec. 1990
Jan. 1991
274
160
175
91
Feb.-April 1991
May-July 1991
Aug.-Oct. 1991
64 (58-70)
57 (49-64)
41 (36-46)
41 (35-46)
42 (37-47)
49 (43-54)
347
141
343
139
166
398
338
Nov.-Dec. 1991
164
Transcribed Image Text:Table 1. Prevalence of HIV-1 in Needles Tested before and during the Syringe-Exchange Program. No. No. HIV- PERCENT HIV-POSITIVE (95% CI) CATEGORY OF NEEDLE TESTED POSITIVE Used before needle exchange, Nov.-Dec. 1990 160 108 68 (60-75) Exchanged illegally 180 113 63 (56-70) Exchanged through the program Nov.-Dec. 1990 Jan. 1991 274 160 175 91 Feb.-April 1991 May-July 1991 Aug.-Oct. 1991 64 (58-70) 57 (49-64) 41 (36-46) 41 (35-46) 42 (37-47) 49 (43-54) 347 141 343 139 166 398 338 Nov.-Dec. 1991 164
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