Suppose a drug molecule binds to a protein target. Complete the table which describes possible noncovalent interactions (N in the binding site. Assume the drug has a variety of types of polar and nonpolar regions. Type of NCI dipole-dipole hydrogen bond polarizability, size; molecular weight ionic interaction Species able to form that NCI any species with permanent dipoles (C-O, etc.) H bonded to N, O, or F and F a dielectric size; type of charge Parameters affecting the NCI ions; charged species strength and orientation of dipole orientation dispersion

Q: 1. O3 2. (CH3)2S or Zn/HOAC

A: To solve this problem we will do ozonolysis of alkene .

Q: A. B. Br MeOH heat NaOEt EtOH

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Q: b. НО Br НО ОН

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Q: Consider the reaction: HCl(9) + NH3 (g) →NH4Cl(s) Using standard thermodynamic data at 298 K,…

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Q: Me OH Ph 1) Me Si(CI)CH₂Br, Et N 2) BuzSnH, AIBN, heat 3) KF, H₂O2 Me OH Ph OH

A: The objective of the question is to show the mechanism of the given reaction.The given molecule is…

Q: O MgBr 1) H₂O H₂SO4 2) HCI/H₂O 1) BH3/THF 2) H₂O₂/NaOH / H₂O

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Q: Draw the best Lew а. NO b. O3 c. SO3 с.

A: Lewis structures, also called electron-dot structures or electron-dot diagrams, are diagrams that…

Q: 4. On image

A: Given that  Concentration of Pb2+ = 0.0012M  Concentration of Cl- = 0.010M  Ksp = 1.6× 10-6

Q: Sclect all the true statements. ||The CI and Br ions have the same number of clectrons,

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Q: Description of atom Evidence supporting model or explained by the model Picture of atom J.J.…

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Q: 1. How many different types of protons does each molecule contain? Please label them. Br b. c. CI Br…

A: Given compounds: We have to find the number of different types of protons each compound has.

Q: CrOp L CI puridino

A:

Q: IZ OH -OH H3O (trace) H2O ? IZ HO HN. -OH но- HN. -OH

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Q: Why is it minus HNO3 for the delta H and not plus? Wouldn't we add them?

A: As we know that the enthalpy change ( ∆H° ) of a reaction is the difference of the standard…

Q: CH₂ DZHO 2) NBS 3) NACK (NO₂ 4) H₂O/Ht

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Q: which of the following activation would afford 1 and 2 respectively? HỌ 1. activation H₂CO WH…

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Q: 4. Determine the moles of HCl required to neutralize Mg(OH)2 (total – excess) and thus the moles…

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Q: Which pKa value best represents the indicated hydrogen? time H 20 15 none of these 25 30

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Q: 1. How many different types of H atoms do you see in each compound? Please label H atoms in…

A: Given

Q: j. H- -H-

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Q: Rank these confirmations from least to most stable ( H. H Br Br. tCH3 H3CtH H,C HHC CH, H. H. H,C H.…

A: We are given the different conformation of a molecule.

Q: the neaks at 105 and 198 amu? in the peak at 272 amu?

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Q: Br 1) NaCN, DMSO 2) excess LАН 3) Н20

A: We have given the organic reaction and we have to find the major product of the reaction.

Q: 1 a. b. C. d. e. f. g. CH3OH C₂H5OH H3C H3C HBr 1. NaH HO CH3 2. C₂H5CI -CH3 H3C- H- CH3 -H -CH3…

A: As per rule we will solve first three sub-parts of the question, Kindly repost other parts as a…

Q: How are the two BRs related and how are the OH figures related

A: Diastereomers: it is defined as non-mirror image, non-identical stereoisomers. An enantiomer also…