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Solid Dosage Manufacturing Facility Facility Description: The new facility will be constructed in Shanghai, China.  The facility will be located in an industrial park area that will provide potable water, waste water and electrical services to the facility. All other utilities will need to be generated at the facility.  The facility will need to support the existing product line described above.  It will also need to provide an additional 25% capacity across all unit operations. The layout and the overall architecture need to support the additional capacity. The equipment will not be purchased initially for the additional capacity. The utility design should consider alternative approaches to support additional capacity at a later date if possible. The site will be sending the tablets and capsules to another facility for packaging so do not include packaging facility design, but include the intermediate storage and transportation requirement to the packaging facility in Brussels, Belgium  for EU market. Assume facility operates 7 days a week and 24 hours per day with three shifts.

Solid Dosage Manufacturing Facility Facility Description: The new facility will be constructed in Shanghai, China.  The facility will be located in an industrial park area that will provide potable water, waste water and electrical services to the facility. All other utilities will need to be generated at the facility.  The facility will need to support the existing product line described above.  It will also need to provide an additional 25% capacity across all unit operations. The layout and the overall architecture need to support the additional capacity. The equipment will not be purchased initially for the additional capacity. The utility design should consider alternative approaches to support additional capacity at a later date if possible. The site will be sending the tablets and capsules to another facility for packaging so do not include packaging facility design, but include the intermediate storage and transportation requirement to the packaging facility in Brussels, Belgium  for EU market. Assume facility operates 7 days a week and 24 hours per day with three shifts.

Introduction to Chemical Engineering Thermodynamics
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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Solid Dosage Manufacturing Facility

Facility Description:

The new facility will be constructed in Shanghai, China.  The facility will be located in an industrial park area that will provide potable water, waste water and electrical services to the facility. All other utilities will need to be generated at the facility. 

The facility will need to support the existing product line described above.  It will also need to provide an additional 25% capacity across all unit operations. The layout and the overall architecture need to support the additional capacity. The equipment will not be purchased initially for the additional capacity. The utility design should consider alternative approaches to support additional capacity at a later date if possible.

The site will be sending the tablets and capsules to another facility for packaging so do not include packaging facility design, but include the intermediate storage and transportation requirement to the packaging facility in Brussels, Belgium  for EU market.

Assume facility operates 7 days a week and 24 hours per day with three shifts.

Class Project: Solid Dosage Manufacturing Facility Product Description: This facility will be making five products; 3 tablets and two capsules Characteristics Tablet 1 Tablet 2 Tablet 3 Capsule 1 Capsule 2 Active A B A Ingredient Product 20 mg 40 mg 10 mg 30 mg 10 mg Configuration Volume 500 million/yr 300million/yr 800 million/yr 300 million/yr 600 million/yr Granulation Wet Wet Dry NA NA Process 10000 per 10000 per 10000 per 5000 per hour 5000 per hour Tablet Press/Capsule hour Filling Speed hour hour No NA NA Yes Tablet Coating Yes Process Description: Tablet 1 and 2 DISPENSING RAW MATERIALS VISUAL INSPECTION WET COMPRESS TABLET COAT MILL BLEND GRANULATE Tablet 3
Transcribed Image Text:Class Project: Solid Dosage Manufacturing Facility Product Description: This facility will be making five products; 3 tablets and two capsules Characteristics Tablet 1 Tablet 2 Tablet 3 Capsule 1 Capsule 2 Active A B A Ingredient Product 20 mg 40 mg 10 mg 30 mg 10 mg Configuration Volume 500 million/yr 300million/yr 800 million/yr 300 million/yr 600 million/yr Granulation Wet Wet Dry NA NA Process 10000 per 10000 per 10000 per 5000 per hour 5000 per hour Tablet Press/Capsule hour Filling Speed hour hour No NA NA Yes Tablet Coating Yes Process Description: Tablet 1 and 2 DISPENSING RAW MATERIALS VISUAL INSPECTION WET COMPRESS TABLET COAT MILL BLEND GRANULATE Tablet 3
DISPENSING RAW MATERIALS DRY BLEND MATERIALS GRANULATE BLEND COMPRESS TABLET COAT VISUAL INSPECTION Capsule 1 and 2 DISPENSING BLEND MATERIALS CAPSULE RAW MATERIALS CAPSULE POLISHING VISUAL INSPECTION FILL Facility Description: The new facility will be constructed in Shanghai, China. The facility will be located in an industrial park area that will provide potable water, waste water and electrical services to the facility. All other utilities will need to be generated at the facility. The facility will need to support the existing product line described above. It will also need to provide an additional 25% capacity across all unit operations. The layout and the overall architecture need to support the additional capacity. The equipment will not be purchased initially for the additional capacity. The utility design should consider alternative approaches to support additional capacity at a later date if possible. The site will be sending the tablets and capsules to another facility for packaging so do not include packaging facility design, but include the intermediate storage and transportation requirement to the packaging facility in Brussels, Belgium for EU market. Assume facility operates 7 days a week and 24 hours per day with three shifts.
Transcribed Image Text:DISPENSING RAW MATERIALS DRY BLEND MATERIALS GRANULATE BLEND COMPRESS TABLET COAT VISUAL INSPECTION Capsule 1 and 2 DISPENSING BLEND MATERIALS CAPSULE RAW MATERIALS CAPSULE POLISHING VISUAL INSPECTION FILL Facility Description: The new facility will be constructed in Shanghai, China. The facility will be located in an industrial park area that will provide potable water, waste water and electrical services to the facility. All other utilities will need to be generated at the facility. The facility will need to support the existing product line described above. It will also need to provide an additional 25% capacity across all unit operations. The layout and the overall architecture need to support the additional capacity. The equipment will not be purchased initially for the additional capacity. The utility design should consider alternative approaches to support additional capacity at a later date if possible. The site will be sending the tablets and capsules to another facility for packaging so do not include packaging facility design, but include the intermediate storage and transportation requirement to the packaging facility in Brussels, Belgium for EU market. Assume facility operates 7 days a week and 24 hours per day with three shifts.
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