Silent mutations that occur in DNA are quite common in living cells and usually involve no effects on phenotype. In not more than 2 pages (using 1.5 line space of Arial or Times New Roman fonts) provide answers for the following questions? 1) Define the silent mutation in DNA? 2) What is the codon usage bias? 3) Provide one example of a clinical implication of a “silent mutation” that proven to have an effect on the phenotype andprovide a brief description of its molecular characteristics? (Explain in details)

Q: An individual carries a disease-causing point mutation. Briefly describe four methods that can be…

A: Point mutation is a type of mutation that results in the alteration of a single base pair. This type…

Q: Genes with highly similar sequence are often located adjacent one another in the genome. Gene…

A: Linked genes are genes that are tightly placed on the same chromosome and tend to inherit together.…

Q: A microbiologist discovers a new type II restriction endonuclease. When DNA is digested by this…

A: Restriction enzymes are also known as molecular scissors because they cut the DNA at specific, short…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: People who carry a theoretical genetic disorder (called B-disease) can be identified from a 2kb DNA…

A: Single nucleotide polymorphism refers to the change in a single nucleotide like adenine (A), guanine…

Q: Explain TWO (2) differences between two commonly used ligases; F. coli DNA ligase and T4 DNA ligase.

A: During DNA cloning process , various restriction enzymes like exonucleases and endonuclease as well…

Q: A nonsynonymous mutation is also referred to as missense mutation. Which of the following correctly…

A: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to external…

Q: Consider the following coding 71 nucleotide DNA template sequence (It does not contain a…

A: In cell protein formed according to the sequence on mRNA. mRNA is formed from DNA sequence by the…

Q: Gene mutations can be classified in two major ways: (1) hereditary or germline mutations that are…

A: Gene is the sequence of nucleotides that encode a particular protein.

Q: Find non-cancerous, non--nonsense, point mutation genetic disease. Describe the disease's name and…

A: A point mutation is a mutation that only affects a single nucleotide of nucleic acid. It occurs most…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: Define FOUR (4) types of point mutations within coding sequences

A: Coding sequences are the sequence of nucleotides in DNA capable to produce a protein. Many mutations…

Q: People who carry a theoretical genetic disorder (called B-disease) can be identified from a 2kb DNA…

A: The SNP is single-nucleotide polymorphism is a variation of DNA sequence that occurs when single…

Q: It has been noted that most transposons in humans and other organisms are located in noncoding…

A: Transposons: Transposons are also referred to as "jumping genes" in which they have the ability to…

Q: You are working with a newly discovered mutagen, and you wish to determine the base change that it…

A: Mutagens often cause alterations in the DNA by changing bases. Substitutions are common examples…

Q: Silent mutations that occur in DNA are quite common in living cells and usually involve no effects…

A: silent mutation is a type of point mutation in DNA that doesn't show any observable effect on the…

Q: please solve the  following: (a)Explain how a mutation effects a genotype. (b) Explain how a…

A: The genotype refers to the hereditary material passed among generation, and the phenotype is…

Q: three different types of loss of function mutations and in each case explain how the mutation exerts…

A: A mutation is any alteration of the base sequence of the DNA or RNA. Since mutation alters the base…

Q: Human wildtype and mutant alleles are identical in sequence except for a single base-pair…

A: A mutation is any change in the DNA sequence of a cell. It may alter one or a few base pairs or…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.