Sickle cell anemia is a disease caused by a mutation at the genotypic level. A person with two copies of the gene has the disease, but a person with one copy of the gene does not have the disease. The diagram shows how this mutation affects an organism. Use the image to answer the question. What type of change occurred in the DNA? A. deletion mutation B. frameshift mutation C. insertion mutation D. substitution mutation
Sickle cell anemia is a disease caused by a mutation at the genotypic level. A person with two copies of the gene has the disease, but a person with one copy of the gene does not have the disease. The diagram shows how this mutation affects an organism. Use the image to answer the question. What type of change occurred in the DNA? A. deletion mutation B. frameshift mutation C. insertion mutation D. substitution mutation
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Sickle cell anemia is a disease caused by a mutation at the genotypic level. A person with two copies of the gene has the disease, but a person with one copy of the gene does not have the disease. The diagram shows how this mutation affects an organism.
Use the image to answer the question.
What type of change occurred in the DNA?
A.
deletion mutation
-
B.
frameshift mutation
-
C.
insertion mutation
-
D.
substitution mutation

Transcribed Image Text:Wild-type B-globin
Sickle-cell B-globin
Wild-type B-globin DNA
CTC
GAG
Mutant B-globin DNA
5'
13'
3'
31
CAC
15'
5
GTG
13'
MRNA
5'1
MRNA
5'
GAG
13'
GUG
13'
Normal hemoglobin
Sickle-cell hemoglobin
Val
Glu
s in
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