Shown below is a logD graph of one of the drugs shown below. Which of the drigs best represents this graph? base LogD Answer: 3.5 pH 0. 1 2 3 4 5 6 7 8 9 0 11 12 13 -1.5 HO CH3 N-CH3 HO CH3 CH3 H3C CH CI COOH .CH3 H3C NH A C D OH OH ČH3 Problem 3b. Draw the LogD vs. pH graph for compound C

General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter10: Acids, Bases, And Salts
Section: Chapter Questions
Problem 10.71EP
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Shown below is a logD graph of one of the drugs shown below. Which of the
drigs best represents this graph?
base
LogD
Answer:
3.5
pH
1 2 3 45 6 7 8 9 10 11 12 13
-1.5
но.
CH3
CH3
H3C
N-CH3 HO.
CH3
COOH
CH; H3C
A
CH;
C
D OH
OH
Problem 3b. Draw the LogD vs. pH graph for compound C
Transcribed Image Text:Shown below is a logD graph of one of the drugs shown below. Which of the drigs best represents this graph? base LogD Answer: 3.5 pH 1 2 3 45 6 7 8 9 10 11 12 13 -1.5 но. CH3 CH3 H3C N-CH3 HO. CH3 COOH CH; H3C A CH; C D OH OH Problem 3b. Draw the LogD vs. pH graph for compound C
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