Show the 6-step reaction mechanism of Pfitzinger synthesis of acetylbiphenyl quinoline carboxylic acid from isatin and acetylbiphenyl. (isatin + NaOH with 4-acetylbiphenyl and ethanol; extract acidified by acetic acid) (Include arrows)
Show the 6-step reaction mechanism of Pfitzinger synthesis of acetylbiphenyl quinoline carboxylic acid from isatin and acetylbiphenyl. (isatin + NaOH with 4-acetylbiphenyl and ethanol; extract acidified by acetic acid) (Include arrows)
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter18: Carboxylic Acids
Section: Chapter Questions
Problem 18.9P
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Question
Show the 6-step reaction mechanism of Pfitzinger synthesis of acetylbiphenyl quinoline
(Include arrows)
![OH
4-Acetylbiphenyl
Isatin
Acetylbiphenyl quinoline carboxylic acid](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F68e19c9a-b34c-43ae-bf98-9ef7b2de301d%2F026649a2-c51f-4353-91ef-52f2dbade4b5%2Fkyoz3oj_processed.png&w=3840&q=75)
Transcribed Image Text:OH
4-Acetylbiphenyl
Isatin
Acetylbiphenyl quinoline carboxylic acid
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