Several enzymes, for example, hepatic lipase and lipoprotein lipase, can bind to lipoproteins. There are mutant variants of these enzymes that bind lipoproteins but are not catalytically active. Cells expressing these mutants can still absorb cholesterol. What does that tell us about the functions of these proteins in cholesterol absorption? A. The proteins are acting as receptors for lipoproteins B. Hydrolysis of neutral lipids is not required C.A and B D. None of the above

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 20P: Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have...
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Several enzymes, for example, hepatic lipase and lipoprotein lipase, can bind to lipoproteins. There are mutant variants
of these enzymes that bind lipoproteins but are not catalytically active. Cells expressing these mutants can still absorb
cholesterol. What does that tell us about the functions of these proteins in cholesterol absorption?
A. The proteins are acting as receptors for lipoproteins
B. Hydrolysis of neutral lipids is not required
C. A and B
D. None of the above
Transcribed Image Text:Several enzymes, for example, hepatic lipase and lipoprotein lipase, can bind to lipoproteins. There are mutant variants of these enzymes that bind lipoproteins but are not catalytically active. Cells expressing these mutants can still absorb cholesterol. What does that tell us about the functions of these proteins in cholesterol absorption? A. The proteins are acting as receptors for lipoproteins B. Hydrolysis of neutral lipids is not required C. A and B D. None of the above
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